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Sites of regulated phosphorylation that control K-Cl cotransporter activity

Sites of regulated phosphorylation that control K-Cl cotransporter activity

http://www.wikidata.org/entity/Q33609638

about

Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission Similar effects of all WNK3 variants on SLC12 cotransporters WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4 PHOSIDA 2011: the posttranslational modification database SNARE-dependent upregulation of potassium chloride co-transporter 2 activity after metabotropic zinc receptor activation in rat cortical neurons in vitro Large-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubule Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents Development and regulation of chloride homeostasis in the central nervous system K-Cl cotransporters, cell volume homeostasis, and neurological disease Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2 Current view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2 Diffusion dynamics of synaptic molecules during inhibitory postsynaptic plasticity Molecular and evolutionary insights into the structural organization of cation chloride cotransporters Molecular motions involved in Na-K-Cl cotransporter-mediated ion transport and transporter activation revealed by internal cross-linking between transmembrane domains 10 and 11/12.Reactive Neurogenesis and Down-Regulation of the Potassium-Chloride Cotransporter KCC2 in the Cochlear Nuclei after Cochlear Deafferentation.A novel regulatory locus of phosphorylation in the C terminus of the potassium chloride cotransporter KCC2 that interferes with N-ethylmaleimide or staurosporine-mediated activation.Mutations affecting GABAergic signaling in seizures and epilepsy.Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4.The emerging role of KCl cotransport in tumor biology.Opposite temperature effect on transport activity of KCC2/KCC4 and N(K)CCs in HEK-293 cells Regulation of with-no-lysine kinase signaling by Kelch-like proteins.Glycoprotein capture and quantitative phosphoproteomics indicate coordinated regulation of cell migration upon lysophosphatidic acid stimulation.Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.Mining recent brain proteomic databases for ion channel phosphosite nuggets.Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation WNK1/HSN2 mutation in human peripheral neuropathy deregulates KCC2 expression and posterior lateral line development in zebrafish (Danio rerio)The WNKs: atypical protein kinases with pleiotropic actions.Comparative analysis of the expression profile of Wnk1 and Wnk1/Hsn2 splice variants in developing and adult mouse tissues.Cation-chloride cotransporters in neuronal development, plasticity and disease STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy.Generation of WNK1 knockout cell lines by CRISPR/Cas-mediated genome editing.KCC2 activity is critical in limiting the onset and severity of status epilepticus.Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons.Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).Role of an apical K,Cl cotransporter in urine formation by renal tubules of the yellow fever mosquito (Aedes aegypti).Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor Regulatory activation is accompanied by movement in the C terminus of the Na-K-Cl cotransporter (NKCC1).

P2860

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P2860

Sites of regulated phosphorylation that control K-Cl cotransporter activity

http://www.wikidata.org/entity/Q33609638

description

2009 nî lūn-bûn

@nan

2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@ast

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@en

type

label

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@ast

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@en

prefLabel

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@ast

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@en

P1433

Q33609638-4E2CD33D-3151-4ED5-917F-19B034A26948

P1476

Q33609638-8724B2C0-0F2E-4C45-8CBB-17688C8DEA6D

P2093

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Q33609638-08D91BCA-6CE2-42E9-AB6B-31FB67EFAD39

Q33609638-09E7817D-C2D8-4CC4-B3BC-B966E106E6FF

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P2860

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P304

Q33609638-5ED1FD80-7BB5-4491-B32E-6EE3273CC78B

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P433

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P478

Q33609638-32B42113-A7CA-4DFE-A6E1-D2A1A6B8571E

P577

Q33609638-5E3AC3E2-08F0-43DC-A768-97261A72420E

P5875

Q33609638-55B358C9-37F0-45A8-968A-229DD13207E5

P698

Q33609638-6599478B-6612-4A48-A7BB-80D74FADCB74

P921

Q33609638-F936ADAF-DD69-4B72-B694-230263A31592

P932

Q33609638-02580B30-8E57-49CD-948C-A6F695DC08D8

P356

J.CELL.2009.05.031

P1433

P1476

Sites of regulated phosphorylation that control K-Cl cotransporter activity

@en

P2093

Biff Forbush

http://www.w3.org/2001/XMLSchema#string

Caleb A Hodson

http://www.w3.org/2001/XMLSchema#string

Christopher M Colangelo

http://www.w3.org/2001/XMLSchema#string

Clinton H Joiner

http://www.w3.org/2001/XMLSchema#string

Dianqing Wu

http://www.w3.org/2001/XMLSchema#string

Erol E Gulcicek

http://www.w3.org/2001/XMLSchema#string

Jesse Rinehart

http://www.w3.org/2001/XMLSchema#string

Jessica E Tanis

http://www.w3.org/2001/XMLSchema#string

Junhui Zhang

http://www.w3.org/2001/XMLSchema#string

Kathryn L Stone

http://www.w3.org/2001/XMLSchema#string

P2860

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1

TreeFam: a curated database of phylogenetic trees of animal gene families

Probability-based protein identification by searching sequence databases using mass spectrometry data

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

The Na-K-Cl cotransporter of secretory epithelia

Human hypertension caused by mutations in WNK kinases

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

P304

525-536

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P31

scholarly article

P356

10.1016/J.CELL.2009.05.031

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P407

P433

3

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P478

138

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P577

2009-08-01T00:00:00Z

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P5875

26727853

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P698

19665974

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P921

phosphorylation

P932

2811214

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