PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways. - Wikidata - wikimedia - TriplyDB

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

http://www.wikidata.org/entity/Q33635465

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PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.Parp3 negatively regulates immunoglobulin class switch recombination.53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks.Identification and Functional Characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in Human Poly(ADP-ribose) Polymerase 3.PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage Repair Pathway Choices and Consequences at the Double-Strand Break PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis.Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin.PARP3 interacts with FoxM1 to confer glioblastoma cell radioresistance.Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice.PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2)Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks.Reversible mono-ADP-ribosylation of DNA breaks.PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection.Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib.Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation.Astrocyte Dysfunction Induced by Alcohol in Females but Not Males.Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.Base excision repair proteins couple activation-induced cytidine deaminase and endonuclease G during replication stress-induced MLL destabilization.Purification of Recombinant Human PARP-3.Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation.Poly(ADP-ribose) polymerase-3 overexpression is associated with poor prognosis in patients with breast cancer following chemotherapy

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PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

http://www.wikidata.org/entity/Q33635465

description

2014 nî lūn-bûn

@nan

2014 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

@ja

2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

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2014年论文

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name

PARP3 affects the relative con ...... mologous end-joining pathways.

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PARP3 affects the relative con ...... mologous end-joining pathways.

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type

label

PARP3 affects the relative con ...... mologous end-joining pathways.

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PARP3 affects the relative con ...... mologous end-joining pathways.

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prefLabel

PARP3 affects the relative con ...... mologous end-joining pathways.

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PARP3 affects the relative con ...... mologous end-joining pathways.

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Nucleic Acids Research

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PARP3 affects the relative con ...... omologous end-joining pathways

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Anbazhagan Rajendran

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Carole Beck

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Christian Boehler

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Giuditta Illuzzi

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Josée Guirouilh Barbat

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Marie-Elise Bonnet

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Najat Magroun

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Philippe Ronde

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Ralph Scully

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Valérie Schreiber

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P2860

DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

APLF promotes the assembly and activity of non-homologous end joining protein complexes

PARP-3 and APLF function together to accelerate nonhomologous end-joining

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

DNA resection in eukaryotes: deciding how to fix the break

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5616-5632

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scholarly article

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10.1093/NAR/GKU174

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P433

9

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42

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Françoise Dantzer

Laurent R Gauthier

Francois Boussin

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2014-03-05T00:00:00Z

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260561660

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24598253

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Poly(ADP-ribose) polymerase family member 3

positive regulation of double-strand break repair via nonhomologous end joining

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4027158

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