APLF promotes the assembly and activity of non-homologous end joining protein complexes
about
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathwayDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayGenotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancerNonhomologous end joining: a good solution for bad endsPARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complexNon-homologous end joining: emerging themes and unanswered questions.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeNeddylation promotes ubiquitylation and release of Ku from DNA-damage sites.Non-homologous end joining: Common interaction sites and exchange of multiple factors in the DNA repair process.Identification and functional characterization of a Ku-binding motif in aprataxin polynucleotide kinase/phosphatase-like factor (APLF)A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus.Ionizing radiation-induced DNA injury and damage detection in patients with breast cancerDNA double strand break repair via non-homologous end-joining.FASN regulates cellular response to genotoxic treatments by increasing PARP-1 expression and DNA repair activity via NF-κB and SP1An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining.The recognition and removal of cellular poly(ADP-ribose) signals.Non-homologous end joining often uses microhomology: implications for alternative end joining.The spatial organization of non-homologous end joining: from bridging to end joining.Understanding the DNA damage response in order to achieve desired gene editing outcomes in mosquitoes.Mechanisms of human lymphoid chromosomal translocations.New factors in mammalian DNA repair-the chromatin connection.Mechanisms of DNA damage, repair, and mutagenesis.PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2)The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins.Noncoding RNA joins Ku and DNA-PKcs for DNA-break resistance in breast cancerDeficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes.Cloning of canine Ku80 and its localization and accumulation at DNA damage sites.Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.Meta-analysis of DNA double-strand break response kinetics.The role of poly ADP-ribosylation in the first wave of DNA damage response.Nonhomologous DNA End Joining for Repair of DNA Double-Strand Breaks.Enhanced expression of histone chaperone APLF associate with breast cancer.Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attachedDNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface
P2860
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P2860
APLF promotes the assembly and activity of non-homologous end joining protein complexes
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@ast
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en-gb
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@nl
type
label
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@ast
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en-gb
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@nl
prefLabel
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@ast
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en-gb
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@nl
P2093
P2860
P3181
P356
P1433
P1476
APLF promotes the assembly and activity of non-homologous end joining protein complexes
@en
P2093
Gabrielle J Grundy
Katie Manley
Keith W Caldecott
Natasha Iles
Stuart L Rulten
Zhihong Zeng
P2860
P304
P3181
P356
10.1038/EMBOJ.2012.304
P407
P577
2012-11-23T00:00:00Z