Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55. - Wikidata - wikimedia - TriplyDB

Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.

Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.

http://www.wikidata.org/entity/Q33636763

about

Lysophosphatidylinositol Signalling and Metabolic Diseases CB2 and GPR55 Receptors as Therapeutic Targets for Systemic Immune Dysregulation Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.Emerging targets in lipid-based therapy Δ(9)-Tetrahydrocannabinol treatment during human monocyte differentiation reduces macrophage susceptibility to HIV-1 infection The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice.Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.GPR55 deletion in mice leads to age-related ventricular dysfunction and impaired adrenoceptor-mediated inotropic responses.Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis A role for GPR55 in human placental venous endothelial cells.Pharmacological profiling of the hemodynamic effects of cannabinoid ligands: a combined in vitro and in vivo approach The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Periaqueductal Gray Cannabinoid receptors: nomenclature and pharmacological principles New insights on endocannabinoid transmission in psychomotor disorders.GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis.Role of GPR55 during Axon Growth and Target Innervation.The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones A potential role for GPR55 in gastrointestinal functions Endocannabinoids in cerebrovascular regulation.Differential activation of cultured neonatal cardiomyocytes by plasmalemmal versus intracellular G protein-coupled receptor 55.Rod photoreceptors express GPR55 in the adult vervet monkey retina.Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer.Off-target cannabinoid effects mediated by GPR55.Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: relevance for their role in depression and in the actions of CB(1) receptor antagonists.Endocannabinoid System: the Direct and Indirect Involvement in the Memory and Learning Processes-a Short Review.Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors.A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum.The GPR55 antagonist CID16020046 protects against intestinal inflammation.Lysophosphatidylinositol stimulates [³⁵S]GTPγS binding in the rat prefrontal cortex and hippocampus.GPR55 regulates intraepithelial lymphocyte migration dynamics and susceptibility to intestinal damage.The LPI/GPR55 axis enhances human breast cancer cell migration via HBXIP and p-MLC signaling.N-arachidonoyl glycine, another endogenous agonist of GPR55.G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1.The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells.Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity.

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Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.

http://www.wikidata.org/entity/Q33636763

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Minireview: recent development ...... itol-sensitive receptor GPR55.

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Minireview: recent development ...... itol-sensitive receptor GPR55.

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Minireview: recent development ...... itol-sensitive receptor GPR55.

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Minireview: recent development ...... itol-sensitive receptor GPR55.

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Minireview: recent development ...... itol-sensitive receptor GPR55.

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Minireview: recent development ...... itol-sensitive receptor GPR55.

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Molecular Endocrinology

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Minireview: recent development ...... sitol-sensitive receptor GPR55

@en

P2093

Andrew Irving

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Clara Andradas

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Julia Kargl

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Maria Waldhoer

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P2860

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

Lysophosphatidic acid production and action: critical new players in breast cancer initiation and progression

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors

Receptors for acylethanolamides-GPR55 and GPR119

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1835-1848

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scholarly article

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10.1210/ME.2011-1197

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11

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25

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Cristina Sánchez

Nariman Balenga

Christopher M Henstridge

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2011-09-29T00:00:00Z

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51686260

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21964594

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5417173

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