The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.
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The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repairXAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcriptionA novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPACloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicasesTranslocation of Cockayne syndrome group A protein to the nuclear matrix: possible relevance to transcription-coupled DNA repairFunctional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB proteinHuman transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase IICooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress.Cockayne syndrome group B protein enhances elongation by RNA polymerase IIAssociation of human protein-tyrosine phosphatase kappa with members of the armadillo familyIn vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patientsCockayne syndrome: defective repair of transcription?Evolutionary conservation of excision repair in Schizosaccharomyces pombe: evidence for a family of sequences related to the Saccharomyces cerevisiae RAD2 geneCorrection of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH)Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group BStructure and expression of the human XPBC/ERCC-3 gene involved in DNA repair disorders xeroderma pigmentosum and Cockayne's syndromeRecruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexesMolecular and cellular analysis of the DNA repair defect in a patient in xeroderma pigmentosum complementation group D who has the clinical features of xeroderma pigmentosum and Cockayne syndromeClinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3Functional TFIIH is required for UV-induced translocation of CSA to the nuclear matrixRequirement of ELC1 for RNA polymerase II polyubiquitylation and degradation in response to DNA damage in Saccharomyces cerevisiaeEvidence that the transcription elongation function of Rpb9 is involved in transcription-coupled DNA repair in Saccharomyces cerevisiae.The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair.A new connection of mRNP biogenesis and export with transcription-coupled repairThe yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcriptionMolecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) geneRAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage.Modulation of Rad26- and Rpb9-mediated DNA repair by different promoter elements.Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimerThe general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factorDNA repair diseases: What do they tell us about cancer and aging?The cockayne syndrome B protein is essential for neuronal differentiation and neuritogenesisCockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodelingRNA polymerase II elongation complexes containing the Cockayne syndrome group B protein interact with a molecular complex containing the transcription factor IIH components xeroderma pigmentosum B and p62The defect in transcription-coupled repair displayed by a Saccharomyces cerevisiae rad26 mutant is dependent on carbon source and is not associated with a lack of transcriptionRetinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndromeDifferential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermisA novel ERCC6 splicing variant associated with a mild Cockayne syndrome phenotypeThe ERCC6 gene and age-related macular degeneration
P2860
Q22010799-69F54B53-80A3-4DC0-B132-977418720877Q24290089-986A8F05-1465-46A2-B83B-8D85066A4FA7Q24290460-D0BFE61D-97A7-4EFE-908A-FE4C2D2E9E01Q24290499-DA8EE3F4-321B-40F7-A706-E6608DC129ADQ24292134-2818A784-1A6A-4175-8EA3-F4C5D675DBACQ24293604-60A3883F-E328-4D8B-A846-F42D4C1CAE0DQ24314310-14D4EC66-6384-4BCA-AB76-9B04C318C07BQ24316039-082B8983-073B-43F8-8240-1E82CBEDE98BQ24317053-6689A4A1-633F-40AB-94CE-C998A4B857B2Q24321401-B35B7228-4750-4130-BFF5-1B292737ACA8Q24323010-9BD5077D-BBA9-4D09-9ACA-8DE4135E877BQ24532391-6A8FAE03-1F42-4F39-9270-4EFB8810DFFEQ24594537-F24BADA0-61B1-4BEB-B376-D3C0ECA6416EQ24596052-9148BDAF-9A25-4EF8-9689-CAA5D77756E4Q24596325-E20F3184-B475-4295-8EAD-F255B983481FQ24628413-FC3AD8BD-CAC3-409B-B379-ADA42424FC9AQ24644162-8C5A1474-1706-42BC-A8B7-FD86B23538A1Q24672295-DEF2FBF3-6BB9-451D-8477-FCC086334CC1Q24673129-222E777E-5569-48FD-B13B-FB9811CDB603Q24683411-7B995FC2-B7C3-41D0-94CE-E60E9852E40BQ27930029-15B1767E-C95F-47B0-AE12-B5D015F82546Q27930103-3655B93D-EC4E-4667-8686-F13EF02BA2C5Q27930568-7D86F7A6-C549-4871-B96C-EBB3CF242E1AQ27931906-B81E303F-BEAD-4DAD-8D9E-BE24E41C8F3CQ27934367-34792E8F-8A0E-449C-90A6-B8E13F4A2270Q27936483-E06FA27D-4B9A-416A-A9ED-8034CACCAB4DQ27937381-120D6E8A-A7F8-475C-890C-0ACB963C7C9FQ27937572-F2F2CFA4-0DBD-408D-B04C-C3BFCED5DC63Q27939686-26D11CFC-54FC-4120-BCB1-C2BD99C79D99Q28142645-1FDCCD75-B800-42F2-958A-9E5C3E5DA8E1Q28235620-5E170657-362B-496C-A85D-6701D2C0B35FQ28238854-499DDCED-87E3-4E5E-93AC-9704E1ADB5F2Q28240933-49D55A73-D4E5-4DD6-BFB5-373FDDF8A1E8Q28245824-6DAD945F-C8EE-4B1B-8BBB-6EA38FD77EF9Q28285490-94C232BC-CF15-4777-885F-1DFCB3F371F1Q28343951-D43DC0BC-048A-4D90-91B6-B79A1C583192Q28587576-4223261B-4A36-4467-BCFC-9B0DCBDC1AB4Q28593341-66279A9B-BE38-457F-BF6A-4F58C86E6A9BQ28649878-9F7F5021-706C-41FE-B3D3-F108D11D22CBQ28748643-85A8E6E4-D8CC-430F-ACD1-C61502CA2240
P2860
The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
The genetic defect in Cockayne ...... transcriptionally active DNA.
@ast
The genetic defect in Cockayne ...... transcriptionally active DNA.
@en
type
label
The genetic defect in Cockayne ...... transcriptionally active DNA.
@ast
The genetic defect in Cockayne ...... transcriptionally active DNA.
@en
prefLabel
The genetic defect in Cockayne ...... transcriptionally active DNA.
@ast
The genetic defect in Cockayne ...... transcriptionally active DNA.
@en
P2093
P2860
P356
P1476
The genetic defect in Cockayne ...... transcriptionally active DNA.
@en
P2093
A A van Zeeland
A T Natarajan
L H Mullenders
P2860
P304
P356
10.1073/PNAS.87.12.4707
P407
P577
1990-06-01T00:00:00Z