IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
about
The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cellsIL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer CellsHOIL-1L interacting protein (HOIP) is essential for CD40 signalingTranscriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity.Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens.Nfil3 is required for the development of all innate lymphoid cell subsets.Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding.NFIL3/E4BP4 controls type 2 T helper cell cytokine expressionTranscriptional and epigenetic networks of helper T and innate lymphoid cells.NFIL3/E4BP4 is a key transcription factor for CD8α⁺ dendritic cell developmentA distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3.The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor.NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunityThe gene expression response of chronic lymphocytic leukemia cells to IL-4 is specific, depends on ZAP-70 status and is differentially affected by an NFκB inhibitor.Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo.Upregulation of Tim-3 on CD4(+) T cells is associated with Th1/Th2 imbalance in patients with allergic asthma.Lipoxin B₄ promotes the resolution of allergic inflammation in the upper and lower airways of miceTissue-resident natural killer cells and their potential diversityThe effect of PDIA3 gene knockout on the mucosal immune function in IBS rats.Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model.Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody.Recruitment of histone methyltransferase G9a mediates transcriptional repression of Fgf21 gene by E4BP4 protein.Development and maturation of natural killer cellsSurvival factor NFIL3 restricts FOXO-induced gene expression in cancerNfil3-independent lineage maintenance and antiviral response of natural killer cellsGlobal gene regulation during activation of immunoglobulin class switching in human B cells.Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE.NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis.Heterogeneous nuclear ribonucleoprotein A1 regulates rhythmic synthesis of mouse Nfil3 protein via IRES-mediated translationTissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cellsThe role of natural killer cells in sepsis.Evolution of IL4 and pathogen antagonism.NK cell development, homeostasis and function: parallels with CD8⁺ T cells.The circadian clock functions as a potent regulator of allergic reaction.Eosinophil resistance to glucocorticoid-induced apoptosis is mediated by the transcription factor NFIL3.New Frontiers for the NFIL3 bZIP Transcription Factor in Cancer, Metabolism and Beyond.Transcriptional and post-transcriptional regulation of NK cell development and function.E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of BimProtein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.Murine thymic NK cells are distinct from ILC1s and have unique transcription factor requirements.
P2860
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P2860
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@ast
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@en
type
label
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@ast
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@en
prefLabel
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@ast
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@en
P2093
P2860
P356
P1476
IL-4-induced transcription factor NFIL3/E4BP4 controls IgE class switching
@en
P2093
Andreas J Schröder
Deborah M Levy
Geri Traver
Keri Murray
Lisa McKeag
Masaki Kashiwada
Paul B Rothman
Stephen M Canfield
P2860
P304
P356
10.1073/PNAS.0909235107
P407
P577
2009-12-22T00:00:00Z