A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. - Wikidata - wikimedia - TriplyDB

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

http://www.wikidata.org/entity/Q33642615

about

Galectin-3 and Beclin1/Atg6 genes in human cancers: using cDNA tissue panel, qRT-PCR, and logistic regression model to identify cancer cell biomarkers Hypoxia-inducible factors and the response to hypoxic stress State of the science: an update on renal cell carcinoma Identifying druggable disease-modifying gene products Blue-Print Autophagy: Potential for Cancer Treatment Molecular and immunologic markers of kidney cancer-potential applications in predictive, preventive and personalized medicine Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition Autophagy in kidney health and disease.RNA-dependent protein kinase is essential for 2-methoxyestradiol-induced autophagy in osteosarcoma cells Identification of the Lipodepsipeptide MDN-0066, a Novel Inhibitor of VHL/HIF Pathway Produced by a New Pseudomonas Species Autophagic cell death: the story of a misnomer Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells.Methodological approaches in application of synthetic lethality screening towards anticancer therapy Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes.Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.4-Pyridylanilinothiazoles that selectively target von Hippel-Lindau deficient renal cell carcinoma cells by inducing autophagic cell death.N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization.Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.A novel sphingosine kinase inhibitor induces autophagy in tumor cells.MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.The genetic basis of kidney cancer: a metabolic disease RFX1-dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells.Successes and challenges in phenotype-based lead discovery for prion diseases Synthetic lethality: general principles, utility and detection using genetic screens in human cells VHL, the story of a tumour suppressor gene.Collateral Lethality: A new therapeutic strategy in oncology PTEN deficiency mediates a reciprocal response to IGFI and mTOR inhibition.A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells.Upregulation of hypoxia-inducible factors and autophagy in von Hippel-Lindau-associated retinal hemangioblastoma.Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL.Autophagy as a therapeutic target in cancer.Approaches to identifying synthetic lethal interactions in cancer.Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation.TXNDC17 promotes paclitaxel resistance via inducing autophagy in ovarian cancer.Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma Emerging role of autophagy in kidney function, diseases and aging High-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinoma

P2860

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P2860

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

http://www.wikidata.org/entity/Q33642615

description

2008 nî lūn-bûn

@nan

2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@ast

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@en

type

label

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@ast

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@en

prefLabel

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@ast

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@en

P1433

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Q33642615-014E6206-D197-4360-BF8A-303445732242

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Q33642615-208B05F4-EF01-414E-932A-CFDE8E651382

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Q33642615-B7FCAB16-1C7B-45D5-A71B-FD5F2BA3ED78

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P356

J.CCR.2008.06.004

P1433

P1476

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy.

@en

P2093

Amato J Giaccia

http://www.w3.org/2001/XMLSchema#string

Denise A Chan

http://www.w3.org/2001/XMLSchema#string

Michael P Hay

http://www.w3.org/2001/XMLSchema#string

Patrick D Sutphin

http://www.w3.org/2001/XMLSchema#string

Sandra Turcotte

http://www.w3.org/2001/XMLSchema#string

William A Denny

http://www.w3.org/2001/XMLSchema#string

P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting

Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer.

P304

90-102

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scholarly article

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10.1016/J.CCR.2008.06.004

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1

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14

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2008-07-01T00:00:00Z

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5254336

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18598947

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2819422

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