A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog
about
Emerging pharmacotherapies for neurodevelopmental disordersCommonality in Down and fetal alcohol syndromes.Molecular signatures of cardiac defects in Down syndrome lymphoblastoid cell lines suggest altered ciliome and Hedgehog pathways.Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Targets Down Syndrome Candidate Region 1 (DSCR1/RCAN1) to control Neuronal Differentiation.Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.Down syndrome--recent progress and future prospects.Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice.Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndromeTrisomic and allelic differences influence phenotypic variability during development of Down syndrome mice.Morphological integration of soft-tissue facial morphology in Down Syndrome and siblings.Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeuticsChronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice.Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndromeDown syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21.Trisomy 21 and facial developmental instabilityMultiple developmental mechanisms regulate species-specific jaw size.Stem and progenitor cell dysfunction in human trisomies.Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome.Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndromeRAI1 gene mutations: mechanisms of Smith-Magenis syndrome.Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression.Muscle stem cell dysfunction impairs muscle regeneration in a mouse model of Down syndrome.Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons.Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with down syndrome.Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome.The Influence of trisomy 21 on facial form and variability.Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic.Survey of Human Chromosome 21 Gene Expression Effects on Early Development in Danio rerio.Globularization and Domestication
P2860
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P2860
A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@ast
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@en
type
label
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@ast
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@en
prefLabel
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@ast
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@en
P2093
P2860
P1476
A neural crest deficit in Down ...... tic response to Sonic hedgehog
@en
P2093
Colyn C Cain
Justin F VanHorn
Randall J Roper
Roger H Reeves
P2860
P304
P356
10.1016/J.MOD.2008.11.002
P577
2008-11-21T00:00:00Z