Antibody-dependent and -independent protection following intranasal immunization of mice with rotavirus particles
about
Intranasal administration of 2/6-rotavirus-like particles with mutant Escherichia coli heat-labile toxin (LT-R192G) induces antibody-secreting cell responses but not protective immunity in gnotobiotic pigs.Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein.Functional mapping of protective domains and epitopes in the rotavirus VP6 protein.Protective immunity and antibody-secreting cell responses elicited by combined oral attenuated Wa human rotavirus and intranasal Wa 2/6-VLPs with mutant Escherichia coli heat-labile toxin in gnotobiotic pigs.Rotavirus 2/6 virus-like particles administered intranasally in mice, with or without the mucosal adjuvants cholera toxin and Escherichia coli heat-labile toxin, induce a Th1/Th2-like immune response.Protection against aerosolized Yersinia pestis challenge following homologous and heterologous prime-boost with recombinant plague antigens.Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo.Rectal immunization with rotavirus virus-like particles induces systemic and mucosal humoral immune responses and protects mice against rotavirus infection.Norovirus P particle, a novel platform for vaccine development and antibody production.Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidatesEffect of rotavirus strain on the murine model of biliary atresiaWhy does the world need another rotavirus vaccine?Prevention of the murine model of biliary atresia after live rotavirus vaccination of dams.Comparative immunogenicity in mice of rotavirus VP6 tubular structures and virus-like particles.Development of a rotavirus-shedding model in rhesus macaques, using a homologous wild-type rotavirus of a new P genotype.Protection of the villus epithelial cells of the small intestine from rotavirus infection does not require immunoglobulin A.CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).Heterologous protection induced by the inner capsid proteins of rotavirus requires transcytosis of mucosal immunoglobulins.Association of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G).Antibody responses to human rotavirus (HRV) in gnotobiotic pigs following a new prime/boost vaccine strategy using oral attenuated HRV priming and intranasal VP2/6 rotavirus-like particle (VLP) boosting with ISCOM.
P2860
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P2860
Antibody-dependent and -independent protection following intranasal immunization of mice with rotavirus particles
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Antibody-dependent and -indepe ...... mice with rotavirus particles
@ast
Antibody-dependent and -indepe ...... mice with rotavirus particles
@en
type
label
Antibody-dependent and -indepe ...... mice with rotavirus particles
@ast
Antibody-dependent and -indepe ...... mice with rotavirus particles
@en
prefLabel
Antibody-dependent and -indepe ...... mice with rotavirus particles
@ast
Antibody-dependent and -indepe ...... mice with rotavirus particles
@en
P2093
P2860
P1433
P1476
Antibody-dependent and -indepe ...... mice with rotavirus particles
@en
P2093
P2860
P304
P577
1999-09-01T00:00:00Z