Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.
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Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SLissencephaly gene product. Localization in the central nervous system and loss of immunoreactivity in Miller-Dieker syndromeAmyloid precursor protein and amyloid precursor-like protein 2 in cancerGeneral anesthetics and β-amyloid proteinA γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APPAmyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegenerationGenetic variants associated with neurodegenerative Alzheimer disease in natural modelsZyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brainThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseProfiles of amyloid precursor and presenilin 2-like proteins are correlated during development of the mouse hypothalamusThe lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartmentsIdentification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursorCompetitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and ToxicityDifferential brain expression of the Alzheimer's amyloid precursor proteinA Bacterial Component to Alzheimer’s-Type Dementia Seen via a Systems Biology Approach that Links Iron Dysregulation and Inflammagen Shedding to DiseaseAnti-Viral Properties of Amyloid-β Peptides.Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio.How cholesterol constrains glycolipid conformation for optimal recognition of Alzheimer's beta amyloid peptide (Abeta1-40).Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain.Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brainDifferent configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer diseaseC-terminal cleavage of the amyloid-beta protein precursor at Asp664: a switch associated with Alzheimer's diseaseHistone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor proteinCharacterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes.Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice.Identification and characterization of C-terminal fragments of the beta-amyloid precursor produced in cell cultureUntangling Alzheimer's disease from fibrous lesions of neurofibrillary tangles and senile plaques.The functions of the amyloid precursor protein gene.Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaquesThe beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerizationMitochondrial DNA Sequence Variation Associated With Peripheral Nerve Function in the Elderly.Cerebrospinal Aβ11-x and 17-x levels as indicators of mild cognitive impairment and patients' stratification in Alzheimer's disease.Can misfolded proteins be beneficial? The HAMLET case.Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.Amyloid beta/A4 precursor protein (APP) processing in lysosomes.A critical analysis of postulated pathogenetic mechanisms in amyloidogenesis.Alzheimer's disease neuropathology. Current status of interpretation of lesion development.
P2860
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P2860
Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.
description
1988 nî lūn-bûn
@nan
1988 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Beta-amyloid precursor protein ...... neural and nonneural tissues.
@ast
Beta-amyloid precursor protein ...... neural and nonneural tissues.
@en
type
label
Beta-amyloid precursor protein ...... neural and nonneural tissues.
@ast
Beta-amyloid precursor protein ...... neural and nonneural tissues.
@en
prefLabel
Beta-amyloid precursor protein ...... neural and nonneural tissues.
@ast
Beta-amyloid precursor protein ...... neural and nonneural tissues.
@en
P2093
P2860
P356
P1476
Beta-amyloid precursor protein ...... n neural and nonneural tissues
@en
P2093
C L Joachim
D J Selkoe
E A Vickers
M B Podlisny
T Oltersdorf
P2860
P304
P356
10.1073/PNAS.85.19.7341
P407
P50
P577
1988-10-01T00:00:00Z