Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization

Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization

Item
http://www.wikidata.org/entity/Q34347798
Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's diseaseLRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric StateIndependent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity.Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.Palmitoylated APP Forms Dimers, Cleaved by BACE1.Current advances in the treatment of Alzheimer's disease: focused on considerations targeting Aβ and tau.Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer's disease mice modelPLXNA4 is associated with Alzheimer disease and modulates tau phosphorylationAssociation of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.A Greek Tragedy: The Growing Complexity of Alzheimer Amyloid Precursor Protein Proteolysis.Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites.Transmembrane Substrate Determinants for γ-Secretase Processing of APP CTFβ.AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.
P2860

Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization

Item
http://www.wikidata.org/entity/Q34347798
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Lowering of amyloid beta pepti ...... precursor protein dimerization
@ast
Lowering of amyloid beta pepti ...... precursor protein dimerization
@en
Lowering of amyloid beta pepti ...... precursor protein dimerization
@nl
type
label
Lowering of amyloid beta pepti ...... precursor protein dimerization
@ast
Lowering of amyloid beta pepti ...... precursor protein dimerization
@en
Lowering of amyloid beta pepti ...... precursor protein dimerization
@nl
prefLabel
Lowering of amyloid beta pepti ...... precursor protein dimerization
@ast
Lowering of amyloid beta pepti ...... precursor protein dimerization
@en
Lowering of amyloid beta pepti ...... precursor protein dimerization
@nl
P1433
P1476
P2093
P2860
P304
P31
P433
P478
P50
P577
P698
P932
P1433
P1476
Lowering of amyloid beta pepti ...... precursor protein dimerization
@en
P2093
P2860
P304
P31
P433
P478
P50
P577
P698
P932