Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma. - Wikidata - wikimedia - TriplyDB

Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.

Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.

http://www.wikidata.org/entity/Q33667199

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Targeting cancer using cholesterol conjugates Withaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells Withaferin A inhibits experimental epithelial-mesenchymal transition in MCF-10A cells and suppresses vimentin protein level in vivo in breast tumors.Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cells Antiproliferative withanolides from several solanaceous species.Cytotoxic oleanane-type saponins from Albizia inundata Anti-proliferative withanolides from the Solanaceae: a structure-activity study Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products Antiproliferative withanolides from Datura wrightii.Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways.Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.Molecular targets and mechanisms of cancer prevention and treatment by withaferin a, a naturally occurring steroidal lactone.Withanolides from Jaborosa caulescens var. bipinnatifida.Novel withanolides target medullary thyroid cancer through inhibition of both RET phosphorylation and the mammalian target of rapamycin pathway.Treatment of adult and pediatric high-grade gliomas with Withaferin A: antitumor mechanisms and future perspectives.Induction of cell-specific apoptosis and protection of mice from cancer challenge by a steroid positive compound from Zornia diphylla (L.) Pers.Natural Withanolides in the Treatment of Chronic Diseases.Withanolides are potent novel targeted therapeutic agents against adrenocortical carcinomas.Minor withanolides of Physalis longifolia: structure and cytotoxicity.Chlorinated Withanolides from Withania somnifera.Natural withanolide withaferin A induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation.Cytotoxic withanolide constituents of Physalis longifolia.Analysis of Major Withanolides in Physalis longifolia Nutt. by HPLC-PDA.Novel natural withanolides induce apoptosis and inhibit migration of neuroblastoma cells through down regulation of N-myc and suppression of Akt/mTOR/NF-κB activation.A Review of Promising Natural Chemopreventive Agents for Head and Neck Cancer.The Ethnobotany and Ethnopharmacology of Wild Tomatillos, Physalis longifolia Nutt., and Related Physalis Species: A Review

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P2860

Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.

http://www.wikidata.org/entity/Q33667199

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

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2010年論文

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2010年論文

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2010年论文

@wuu

name

Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

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Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

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type

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Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

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Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

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Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

@ast

Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

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P1433

Journal of Natural Products

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Withaferin A, a cytotoxic ster ...... neck squamous cell carcinoma.

@en

P2093

Abbas K Samadi

http://www.w3.org/2001/XMLSchema#string

Barbara N Timmermann

http://www.w3.org/2001/XMLSchema#string

Huaping Zhang

http://www.w3.org/2001/XMLSchema#string

Mark S Cohen

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Ridhwi Mukerji

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Xiaoqin Tong

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P2860

Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.

Phylogenetics of the florally diverse Andean clade Iochrominae (Solanaceae).

Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study.

Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.

Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.

Withaferin A targets heat shock protein 90 in pancreatic cancer cells.

Differential expression profiling of head and neck squamous cell carcinoma (HNSCC).

Withanolides and related ergostane-type steroids.

Management of locally advanced or unresectable head and neck cancer.

Recent changes in the epidemiology of head and neck cancer.

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1476-1481

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10.1021/NP100112P

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9

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73

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20726569

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2945430

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