Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.
about
Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fosIdentification of a transcription factor that binds to the S box of the I-A beta gene of the major histocompatibility complexDNA binding properties of YB-1 and dbpA: binding to double-stranded, single-stranded, and abasic site containing DNAs.X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.Interferon gamma response region in the promoter of the human DPA gene.Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeletonShared promoter elements between a viral superantigen and the major histocompatibility complex class II-associated invariant chain.Transcription factors induced by interferons alpha and gamma.Regulatory factor-X binding to mutant HLA-DRA promoter sequencesImportance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants.cis-acting sequences required for class II gene regulation by interferon gamma and tumor necrosis factor alpha in a murine macrophage cell line.YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoterTwo cis-DNA elements involved in myeloid-cell-specific expression and gamma interferon (IFN-gamma) activation of the human high-affinity Fc gamma receptor gene: a novel IFN regulatory mechanism.Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function.Sequence elements required for activity of a murine major histocompatibility complex class II promoter bind common and cell-type-specific nuclear factors.Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes.Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family.Identification of cis sequences controlling efficient position-independent tissue-specific expression of human major histocompatibility complex class I genes in transgenic mice.In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma.Human chromosome 16 encodes a factor involved in induction of class II major histocompatibility antigens by interferon gamma.Allele-specific DNA-protein interactions associated with the X-box regulatory region of the DQB1*0302 gene.Transcriptional induction of IFN-gamma-responsive genes is modulated by DNA surrounding the interferon stimulation response element.The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element.Human HLA-DR alpha gene: a rare oligonucleotide (GTATA) identifies an upstream sequence required for nuclear protein binding.Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.Evidence for multiple major histocompatibility class II X-box binding proteins.Identification of the transcription factors NF-YA and NF-YB as factors A and B that bound to the promoter of the major histocompatibility complex class II gene I-A beta.The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA.B-cell factor 1 is required for optimal expression of the DRA promoter in B cells.The presence of a DNA binding complex correlates with E beta class II MHC gene expressionCooperativity between the J and S elements of class II major histocompatibility complex genes as enhancers in normal and class II-negative patient and mutant B cell lines.Dissection of the interferon gamma-MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s).Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes
P2860
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P2860
Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Detailed delineation of an int ...... a glioblastoma multiform line.
@ast
Detailed delineation of an int ...... a glioblastoma multiform line.
@en
type
label
Detailed delineation of an int ...... a glioblastoma multiform line.
@ast
Detailed delineation of an int ...... a glioblastoma multiform line.
@en
prefLabel
Detailed delineation of an int ...... a glioblastoma multiform line.
@ast
Detailed delineation of an int ...... a glioblastoma multiform line.
@en
P2093
P2860
P356
P1476
Detailed delineation of an int ...... a glioblastoma multiform line.
@en
P2093
P2860
P304
P356
10.1073/PNAS.85.22.8618
P407
P577
1988-11-01T00:00:00Z