Dissection of the interferon gamma-MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s).
about
Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor betaRegulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.The MHC class II E beta promoter: a complex arrangement of positive and negative elements determines B cell and interferon-gamma (IFN-gamma) regulated expression.IRF-4-mediated CIITA transcription is blocked by KSHV encoded LANA to inhibit MHC II presentation.Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway.Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon gamma.YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gammaHuman cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway.Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.Low-dose interferon-gamma-producing human neuroblastoma cells show reduced proliferation and delayed tumorigenicity.Class II transactivator regulates the expression of multiple genes involved in antigen presentation.Mutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3 alpha componentsClass II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.In vitro activation of the transcription factor gamma interferon activation factor by gamma interferon: evidence for a tyrosine phosphatase/kinase signaling cascade.
P2860
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P2860
Dissection of the interferon gamma-MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s).
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Dissection of the interferon g ...... ommon signalling component(s).
@en
type
label
Dissection of the interferon g ...... ommon signalling component(s).
@en
prefLabel
Dissection of the interferon g ...... ommon signalling component(s).
@en
P2093
P2860
P1433
P1476
Dissection of the interferon g ...... ommon signalling component(s).
@en
P2093
P2860
P304
P407
P577
1992-04-01T00:00:00Z