A general approach for identifying distant regulatory elements applied to the Gdf6 gene. - Wikidata - wikimedia - TriplyDB

A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

http://www.wikidata.org/entity/Q33679006

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SEARCHING FOR FUNCTIONAL GENETIC VARIANTS IN NON-CODING DNA Misexpression of Six2 is associated with heritable frontonasal dysplasia and renal hypoplasia in 3H1 Br mice Minimal cross-recombination between wild-type and loxP511 sites in vivo facilitates truncating both ends of large DNA inserts in pBACe3.6 and related vectors.Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins Harnessing mobile genetic elements to explore gene regulation Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.SNPs in Multi-species Conserved Sequences (MCS) as useful markers in association studies: a practical approach.Shaping skeletal growth by modular regulatory elements in the Bmp5 gene Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease.Genomic identification of regulatory elements by evolutionary sequence comparison and functional analysis Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes Distal regions of the human IFNG locus direct cell type-specific expression.Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice.The BMP ligand Gdf6 prevents differentiation of coronal suture mesenchyme in early cranial development.A molecular basis for classic blond hair color in Europeans.Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates.Relevance of BAC transgene copy number in mice: transgene copy number variation across multiple transgenic lines and correlations with transgene integrity and expression A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury High temperature requirement factor A1 (HTRA1) gene regulates angiogenesis through transforming growth factor-β family member growth differentiation factor 6.Assessing the functional characteristics of synonymous and nonsynonymous mutation candidates by use of large DNA constructs.Molecular recognition in bone morphogenetic protein (BMP)/receptor interaction.Fishing for function: zebrafish BAC transgenics for functional genomics TGF-beta signaling is essential for joint morphogenesis.Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton A misplaced lncRNA causes brachydactyly in humans.Remote control of gene expression.Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks.Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells BMP-2 vs. BMP-4 expression and activity in glucocorticoid-arrested MC3T3-E1 osteoblasts: Smad signaling, not alkaline phosphatase activity, predicts rescue of mineralization.Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2.Hox11 genes are required for regional patterning and integration of muscle, tendon and bone.BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells.Control of BMP gene expression by long-range regulatory elements.Identifying Distal cis-acting Gene-Regulatory Sequences by Expressing BACs Functionalized with loxP-Tn10 Transposons in Zebrafish.Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk.Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter.Identification of a distant cis-regulatory element controlling pharyngeal arch-specific expression of zebrafish gdf6a/radar Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter.BAC constructs in transgenic reporter mouse lines control efficient and specific LacZ expression in hypertrophic chondrocytes under the complete Col10a1 promoter.

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P2860

A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

http://www.wikidata.org/entity/Q33679006

description

2003 nî lūn-bûn

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2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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type

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A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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prefLabel

A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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Genome Research

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A general approach for identifying distant regulatory elements applied to the Gdf6 gene.

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Catherine Guenther

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David M Kingsley

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Douglas P Mortlock

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P2860

Initial sequencing and comparative analysis of the mouse genome

A human chondrodysplasia due to a mutation in a TGF-beta superfamily member

Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development

The probability of preservation of a newly arisen gene duplicate

Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family

Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord

Deletion of long-range regulatory elements upstream of SOX9 causes campomelic dysplasia

BLAT--the BLAST-like alignment tool

Xenopus GDF6, a new antagonist of noggin and a partner of BMPs

In vitro regulation of expression of cartilage-derived morphogenetic proteins by growth hormone and insulinlike growth factor 1 in the bovine cricoid chondrocyte

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2069-2081

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10.1101/GR.1306003

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12915490

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403689

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