Molecular dosimetry of 1,2,3,4-diepoxybutane-induced DNA-DNA cross-links in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation.
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NanoLC/ESI+ HRMS3 quantitation of DNA adducts induced by 1,3-butadieneExposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadieneBis-butanediol-mercapturic acid (bis-BDMA) as a urinary biomarker of metabolic activation of butadiene to its ultimate carcinogenic species.Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation.Column switching HPLC-ESI(+)-MS/MS methods for quantitative analysis of exocyclic dA adducts in the DNA of laboratory animals exposed to 1,3-butadiene.Major groove orientation of the (2S)-N(6)-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene.Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1,3-butadiene in male C57BL/6J miceEpigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene.The formation and biological significance of N7-guanine adductsQuantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humansDiepoxybutane interstrand cross-links induce DNA bending.NanoHPLC-nanoESI(+)-MS/MS quantitation of bis-N7-guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene.Quantitation of DNA adducts by stable isotope dilution mass spectrometry.1,3-Butadiene: Biomarkers and application to risk assessment.Alcohol dehydrogenase- and rat liver cytosol-dependent bioactivation of 1-chloro-2-hydroxy-3-butene to 1-chloro-3-buten-2-one, a bifunctional alkylating agent.DNA-reactive protein monoepoxides induce cell death and mutagenesis in mammalian cellsMass spectrometry of structurally modified DNA.In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.1,3-Butadiene: I. Review of metabolism and the implications to human health risk assessment.1,3-Butadiene: II. Genotoxicity profile.1,3-Butadiene: III. Assessing carcinogenic modes of action.Isotope Dilution nanoLC/ESI+-HRMS3 Quantitation of Urinary N7-(1-Hydroxy-3-buten-2-yl) Guanine Adducts in Humans and Their Use as Biomarkers of Exposure to 1,3-Butadiene.Alkyltransferase-mediated toxicity of bis-electrophiles in mammalian cells.Conjugation of butadiene diepoxide with glutathione yields DNA adducts in vitro and in vivo.Mutation spectra of S-(2-hydroxy-3,4-epoxybutyl)glutathione: comparison with 1,3-butadiene and its metabolites in the Escherichia coli rpoB gene.Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.
P2860
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P2860
Molecular dosimetry of 1,2,3,4-diepoxybutane-induced DNA-DNA cross-links in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation.
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2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@ast
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@en
type
label
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@ast
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@en
prefLabel
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@ast
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@en
P2093
P2860
P1433
P1476
Molecular dosimetry of 1,2,3,4 ...... o 1,3-butadiene by inhalation.
@en
P2093
James A Swenberg
Melissa Goggin
Natalia Tretyakova
Vernon E Walker
P2860
P304
P356
10.1158/0008-5472.CAN-08-4152
P407
P577
2009-03-10T00:00:00Z