Alcohol dehydrogenase- and rat liver cytosol-dependent bioactivation of 1-chloro-2-hydroxy-3-butene to 1-chloro-3-buten-2-one, a bifunctional alkylating agent.
about
Cytotoxicity, genotoxicity, and mutagenicity of 1-chloro-2-hydroxy-3-butene and 1-chloro-3-buten-2-one, two alternative metabolites of 1,3-butadiene.Formation of fused-ring 2'-deoxycytidine adducts from 1-chloro-3-buten-2-one, an in vitro 1,3-butadiene metabolite, under in vitro physiological conditions.Potential roles of myeloperoxidase and hypochlorous acid in metabolism and toxicity of alkene hydrocarbons and drug molecules containing olefinic moieties.
P2860
Alcohol dehydrogenase- and rat liver cytosol-dependent bioactivation of 1-chloro-2-hydroxy-3-butene to 1-chloro-3-buten-2-one, a bifunctional alkylating agent.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@ast
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@en
type
label
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@ast
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@en
prefLabel
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@ast
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@en
P2860
P356
P1476
Alcohol dehydrogenase- and rat ...... bifunctional alkylating agent.
@en
P2093
Adnan A Elfarra
Xin-Yu Zhang
P2860
P304
P356
10.1021/TX300369B
P577
2012-11-07T00:00:00Z