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Role of S-nitrosylation in apoptosis resistance and carcinogenesisS-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation - a novel antiapoptotic mechanism that suppresses apoptosisNitric oxide-mediated Bcl-2 stabilization potentiates malignant transformation of human lung epithelial cellsApogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivo.Extracts from Vatica diospyroides type SS fruit show low dose activity against MDA-MB-468 breast cancer cell-line via apoptotic actionJacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins.Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.Design, synthesis, and biological evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine and its analogs as a novel class of anticancer agents.Cellular signalling pathways: new targets in leukaemia therapy.Optimization of circulating biomarkers of obatoclax-induced cell death in patients with small cell lung cancer.CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion.Yeast as a model system for anticancer drug discovery.The effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine.Design and Evolution of a Miniature Bcl-2 Binding Protein We thank the HHMI Biopolymer/Keck Foundation Biotechnology Resource Laboratory (Yale University School of Medicine, New Haven, CT) for oligonucleotide and peptide synthesis and amino acid anaInterfacing materials science and biology for drug carrier design.Microarray determination of Bcl-2 family protein inhibition sensitivity in breast cancer cells.3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.Antiproliferative activity of flavonoids: influence of the sequential methoxylation state of the flavonoid structure.FKBP38 protects Bcl-2 from caspase-dependent degradation.A conjugate of the lytic peptide Hecate and gallic acid: structure, activity against cervical cancer, and toxicity.Effect of ethyl acetate aroma on viability of human breast cancer and normal kidney epithelial cells in vitro.Agents that target cysteine residues of biomolecules and their therapeutic potential
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Novel anticancer drug discovery.
@ast
Novel anticancer drug discovery.
@en
type
label
Novel anticancer drug discovery.
@ast
Novel anticancer drug discovery.
@en
prefLabel
Novel anticancer drug discovery.
@ast
Novel anticancer drug discovery.
@en
P1476
Novel anticancer drug discovery.
@en
P2093
Buolamwini JK
P304
P356
10.1016/S1367-5931(99)80073-8
P577
1999-08-01T00:00:00Z