Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

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http://www.wikidata.org/entity/Q34263558
The consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domainA novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.Synthesis of phosphatase-stable, cell-permeable peptidomimetic prodrugs that target the SH2 domain of Stat3Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structureRecent advances in protein tyrosine phosphatase 1B inhibitors.Filarial nematode secreted product ES-62 is an anti-inflammatory agent: therapeutic potential of small molecule derivatives and ES-62 peptide mimetics.Efficient delivery of cell impermeable phosphopeptides by a cyclic peptide amphiphile containing tryptophan and arginineSynthesis and evaluation of tripodal peptide analogues for cellular delivery of phosphopeptidesDevelopment of Grb2 SH2 Domain Signaling Antagonists: A Potential New Class of Antiproliferative AgentsSynthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain.The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease.Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis.Structure-based drug design and AutoDock study of potential protein tyrosine kinase inhibitors.Structure-based design of novel nonpeptide inhibitors of the Src SH2 domain:phosphotyrosine mimetics exploiting multifunctional group replacement chemistry.Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.Identification of a potent inhibitor of human dual-specific phosphatase, VHR, from computer-aided and NMR-based screening to cellular effects.
P2860

Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

Item
http://www.wikidata.org/entity/Q34263558
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@ast
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@en
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@nl
type
label
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@ast
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@en
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@nl
prefLabel
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@ast
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@en
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.
@en
P2093
P2860
P304
P31
P356
10.1002/1097-0282(2001)60:1<32::AID-BIP1002>3.0.CO;2-I
P433
P478
P577
P698