The HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets.
about
Influenza A virus transmission via respiratory aerosols or droplets as it relates to pandemic potentialSpecific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in miceRespiratory transmission of an avian H3N8 influenza virus isolated from a harbour sealMouse lung-adapted mutation of E190G in hemagglutinin from H5N1 influenza virus contributes to attenuation in mice.Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response.In vitro and in vivo characterization of a novel H1N1/2009 influenza virus reassortant with an NS gene from a highly pathogenic H5N1 virus, isolated from a human.Acquisition of human-type receptor binding specificity by new H5N1 influenza virus sublineages during their emergence in birds in Egypt.Characterization of an artificial swine-origin influenza virus with the same gene combination as H1N1/2009 virus: a genesis clue of pandemic strain.An overview of the highly pathogenic H5N1 influenza virus.H5N1 pathogenesis studies in mammalian models.Pathogenesis of Influenza A/H5N1 virus infection in ferrets differs between intranasal and intratracheal routes of inoculationAppearance of L90I and N205S Mutations in Effector Domain of NS1 Gene of pdm (09) H1N1 Virus from India during 2009-2013.The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infectionA single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles.Chicken cyclophilin A is an inhibitory factor to influenza virus replication.Identification of molecular markers associated with alteration of receptor-binding specificity in a novel genotype of highly pathogenic avian influenza A(H5N1) viruses detected in Cambodia in 2013A combination of HA and PA mutations enhances virulence in a mouse-adapted H6N6 influenza A virus.Highly pathogenic H5N1 influenza A virus strains provoke heterogeneous IFN-α/β responses that distinctively affect viral propagation in human cells.Systemic dissemination of H5N1 influenza A viruses in ferrets and hamsters after direct intragastric inoculation.The virulence of 1997 H5N1 influenza viruses in the mouse model is increased by correcting a defect in their NS1 proteins.Insertion of a multibasic cleavage site in the haemagglutinin of human influenza H3N2 virus does not increase pathogenicity in ferretsA complete map of potential pathogenicity markers of avian influenza virus subtype H5 predicted from 11 expressed proteinsIdentification of host genes linked with the survivability of chickens infected with recombinant viruses possessing H5N1 surface antigens from a highly pathogenic avian influenza virus.Fatal Cases of Seasonal Influenza in Russia in 2015-2016New reassortant H5N8 highly pathogenic avian influenza virus from waterfowl in Southern ChinaFunctional characterization of ferret CCL20 and CCR6 and identification of chemotactic inhibitors.Active surveillance for avian influenza virus, Egypt, 2010-2012.Animal models in virus research: their utility and limitations.Characteristics of two highly pathogenic avian influenza H5N8 viruses with different pathogenicity in mice.H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?Influenza A virus-encoded NS1 virulence factor protein inhibits innate immune response by targeting IKK.Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells.Prevalence of the C-terminal truncations of NS1 in avian influenza A viruses and effect on virulence and replication of a highly pathogenic H7N1 virus in chickensInfluenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS.Avian influenza virus NS1: A small protein with diverse and versatile functions.Two highly pathogenic avian influenza H5N1 viruses of clade 2.3.2.1 with similar genetic background but with different pathogenicity in mice and ducks.Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates.Diversity of Influenza A(H5N1) Viruses in Infected Humans, Northern Vietnam, 2004-2010.
P2860
Q28388026-A81CEE21-243F-44C4-8A0F-3FEDC013C13BQ30357662-3CBDAFEF-EDB5-4A55-88F2-1C957B58FD6BQ30366374-11A49748-A548-4DC3-BA15-85F67CCA2892Q30375832-14D12188-4906-4AFB-9494-33BA087BE849Q30397674-CDD1E836-0D93-4A78-9280-97F9441934F3Q30402158-C21CD444-1547-43E5-81BF-1FCF1905A2C1Q30403405-B09309ED-F75D-4362-A006-DAC610E9AB28Q30405348-0EFFC7D3-5E97-4069-A0FA-F0E97AE7835AQ30426011-29CB77F9-B365-4F15-8160-9D624FA5ED39Q30427806-91D603C9-7AFB-448C-9D70-B9649CC26C70Q33922699-0298390D-F42F-4656-B522-F4D8FF2FF7DCQ34275252-E9CB2E67-032F-4F0C-A5D8-D89ABF36E01DQ34413551-90A8BDE3-06BE-4332-A2D7-CD3754354C21Q34469486-FA0F6A11-C3F8-4E50-AFE8-52AC227BA024Q34499110-4A4C9631-61F1-448D-BBC1-A505ACF2FC35Q34594048-FF335821-B99D-4A8F-8BCD-0EF2E52A242FQ34595044-56387659-EB92-424D-9476-1B670A60D95CQ34602475-23C63B2B-3AF9-4950-98C5-3D6F8BC645EFQ35076781-6CFFECDE-CD3D-42A0-BB74-47C6A97CF8F1Q35077820-E146736F-C206-400F-8B7B-07582D7E126FQ35200137-BEC9508A-473E-4660-860A-4D8D26D31521Q35674905-DC8EF227-D1A0-4C0F-88E7-B085DC0D73EFQ35826057-CCCEFB4A-EA12-4CF8-98A6-5D25FF4B8B0FQ36173180-954E17D9-F443-49E9-BD99-12A427AFB71FQ36192230-E3306BF2-59C8-4FF1-99EE-A4544EC61785Q36677825-04DA89C2-D571-4D0E-B49E-CDB9D706DDF9Q37664608-F2347F37-7898-45E5-9855-B9F957E34443Q38043556-8064C49D-5A0A-443A-8E9A-BD01D32C6676Q38748529-0832DB20-5CF2-407F-9E8A-90E6EF1F2029Q38937423-61F9E782-ADEB-4E77-BE45-20471041EB4EQ39297691-0A1EE87C-2084-451E-8027-235F64DDB672Q39355418-064B2297-8951-48B8-B9EF-75EE8A3BB424Q40851229-3763BC35-5751-4931-9538-2FCFEB0CABB0Q42198095-293FA562-5683-43F2-8BC3-D0FBE1AF63D0Q42724653-9D434B44-CD12-49B5-97D8-A9F1B3FBD20DQ43652261-B184D7D0-F834-4597-8B44-DDFACA91C1DCQ55491209-9DCF21C5-7393-45FB-8959-2B66648D88F1Q55555164-303FDE34-233C-4869-80EB-F6584369626B
P2860
The HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The HA and NS genes of human H ...... to high virulence in ferrets.
@ast
The HA and NS genes of human H ...... to high virulence in ferrets.
@en
type
label
The HA and NS genes of human H ...... to high virulence in ferrets.
@ast
The HA and NS genes of human H ...... to high virulence in ferrets.
@en
prefLabel
The HA and NS genes of human H ...... to high virulence in ferrets.
@ast
The HA and NS genes of human H ...... to high virulence in ferrets.
@en
P2093
P2860
P50
P1433
P1476
The HA and NS genes of human H ...... to high virulence in ferrets.
@en
P2093
Chairul A Nidom
Hideo Goto
Hirotaka Imai
Kei Takahashi
Kyoko Shinya
Mai Thi Quynh Le
Masayuki Shimojima
Mutsumi Ito
Ryo Takano
P2860
P304
P356
10.1371/JOURNAL.PPAT.1001106
P577
2010-09-16T00:00:00Z