Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients - Wikidata - wikimedia - TriplyDB

Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients

Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients

http://www.wikidata.org/entity/Q33703923

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Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus The role of genetic variation near interferon-kappa in systemic lupus erythematosus IRF7: activation, regulation, modification and function Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus Clinical perspectives on lupus genetics: advances and opportunities Advances in lupus genetics Familial aggregation of autoimmune disease in juvenile dermatomyositis IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus Emerging therapies for systemic lupus erythematosus--focus on targeting interferon-alpha Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data.Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.Mapping eQTLs with RNA-seq reveals novel susceptibility genes, non-coding RNAs and alternative-splicing events in systemic lupus erythematosus The unexplained female predominance of systemic lupus erythematosus: clues from genetic and cytokine studies.Promoter variant of PIK3C3 is associated with autoimmunity against Ro and Sm epitopes in African-American lupus patients.Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus.Activation of type I interferon pathway in systemic lupus erythematosus: association with distinct clinical phenotypes.Toll-like receptor 7 stimulates the expression of Epstein-Barr virus latent membrane protein 1 Advances in lupus genetics and epigenetics Association of a functional IRF7 variant with systemic lupus erythematosus.Murine lupus susceptibility locus Sle2 activates DNA-reactive B cells through two sub-loci with distinct phenotypes Interferon regulatory factors in human lupus pathogenesis Interferon regulatory factors: critical mediators of human lupus.Genetic susceptibility to systemic lupus erythematosus in the genomic era Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.Interferon alpha as a primary pathogenic factor in human lupus Targeting interferon regulatory factors to inhibit activation of the type I IFN response: implications for treatment of autoimmune disorders.The autoimmune disease risk allele of UBE2L3 in African American patients with systemic lupus erythematosus: a recessive effect upon subphenotypes.Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients.Cofactors required for TLR7- and TLR9-dependent innate immune responses Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing.Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis Myeloid dendritic cells from B6.NZM Sle1/Sle2/Sle3 lupus-prone mice express an IFN signature that precedes disease onset A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients.Gene-expression-guided selection of candidate loci and molecular phenotype analyses enhance genetic discovery in systemic lupus erythematosus.Immunogenetics of systemic lupus erythematosus: A comprehensive review.Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway.Genetics of Lupus Nephritis: Clinical Implications.

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Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients

http://www.wikidata.org/entity/Q33703923

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Genetic variation at the IRF7/ ...... pha activity in lupus patients

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Genetic variation at the IRF7/ ...... pha activity in lupus patients

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Genetic variation at the IRF7/ ...... pha activity in lupus patients

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Genetic variation at the IRF7/ ...... pha activity in lupus patients

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Genetic variation at the IRF7/ ...... pha activity in lupus patients

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Genetic variation at the IRF7/ ...... pha activity in lupus patients

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Arthritis and Rheumatism

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Genetic variation at the IRF7/ ...... pha activity in lupus patients

@en

P2093

Beverly S Franek

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Lesley Rhee

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Meenakshi Jolly

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Rachel A Mikolaitis

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Rafah Salloum

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Tammy O Utset

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P2860

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

A haplotype map of the human genome

Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection

Interferon alpha-induced lupus: proof of principle

High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

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553-561

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10.1002/ART.27182

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2

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62

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Timothy B. Niewold

Silvia N Kariuki

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2010-02-01T00:00:00Z

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41175617

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20112359

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