Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. - Wikidata - wikimedia - TriplyDB

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

http://www.wikidata.org/entity/Q33705076

about

Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2 XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair Epigenetic modifications in double-strand break DNA damage signaling and repair Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Beyond DNA repair: DNA-PK function in cancer What goes on must come off: phosphatases gate-crash the DNA damage response Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines.The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis Roles of ChlR1 DNA helicase in replication recovery from DNA damage Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length Interactome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication.Protein Ser/Thr phosphatase-6 is required for maintenance of E-cadherin at adherens junctions.Valosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells.PP6 regulatory subunit R1 is bidentate anchor for targeting protein phosphatase-6 to DNA-dependent protein kinase Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma Protein Ser/Thr phosphatases--the ugly ducklings of cell signalling.A PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis.Family-specific, novel, deleterious germline variants provide a rich resource to identify genetic predispositions for BRCAx familial breast cancer.Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis.Phosphatases in the cellular response to DNA damage.Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage.Histone phosphorylation: a chromatin modification involved in diverse nuclear events.Regulation of ATM/DNA-PKcs Phosphorylation by BRCA1-Associated BAAT1.Protein phosphatase PP6 is required for homology-directed repair of DNA double-strand breaks Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures.TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response.Cajal body proteins differentially affect the processing of box C/D scaRNPs.Adaptation of HepG2 cells to a steady-state reduction in the content of protein phosphatase 6 (PP6) catalytic subunit TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis.H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues.Gamma-H2AX upregulation caused by Wip1 deficiency increases depression-related cellular senescence in hippocampus.Tracheal Morphologic and Protein Alterations FollowingShort-Term Cigarette Mainstream Smoke Exposure to Rats Protein Phosphatase 6 Protects Prophase I-Arrested Oocytes by Safeguarding Genomic Integrity Quantitative fragmentome mapping reveals novel, domain-specific partners for the modular protein RepoMan (recruits PP1 onto mitotic chromatin at anaphase).Focus on histone variant H2AX: to be or not to be.Multifaceted roles of Arabidopsis PP6 phosphatase in regulating cellular signaling and plant development.

P2860

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P2860

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

http://www.wikidata.org/entity/Q33705076

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Protein phosphatase 6 interact ...... d dephosphorylates gamma-H2AX.

@ast

Protein phosphatase 6 interact ...... d dephosphorylates gamma-H2AX.

@en

type

label

Protein phosphatase 6 interact ...... d dephosphorylates gamma-H2AX.

@ast

Protein phosphatase 6 interact ...... d dephosphorylates gamma-H2AX.

@en

prefLabel

Protein phosphatase 6 interact ...... d dephosphorylates gamma-H2AX.

@ast

Protein phosphatase 6 interact ...... d dephosphorylates gamma-H2AX.

@en

P1433

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P1433

Molecular and Cellular Biology

P1476

Protein phosphatase 6 interact ...... nd dephosphorylates gamma-H2AX

@en

P2093

Greg B G Moorhead

http://www.w3.org/2001/XMLSchema#string

Jianing Zhong

http://www.w3.org/2001/XMLSchema#string

Pauline Douglas

http://www.w3.org/2001/XMLSchema#string

Ruiqiong Ye

http://www.w3.org/2001/XMLSchema#string

Susan P Lees-Miller

http://www.w3.org/2001/XMLSchema#string

P2860

A probability-based approach for high-throughput protein phosphorylation analysis and site localization

Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon

Large-scale characterization of HeLa cell nuclear phosphoproteins

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Alpha 4 associates with protein phosphatases 2A, 4, and 6

PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4

Nonhomologous end joining and V(D)J recombination require an additional factor

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication

P304

1368-1381

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scholarly article

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10.1128/MCB.00741-09

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P407

P433

6

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P478

30

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2010-01-11T00:00:00Z

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20065038

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2832507

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