XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
about
The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiencyThe mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayFunctional significance of the interaction with Ku in DNA double-strand break recognition of XLFBiochemical characterization of metnase's endonuclease activity and its role in NHEJ repairKu recruits XLF to DNA double-strand breaksAPLF promotes the assembly and activity of non-homologous end joining protein complexesDNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repairInteractome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathwayXLS (c9orf142) is a new component of mammalian DNA double-stranded break repairATM damage response and XLF repair factor are functionally redundant in joining DNA breaksThe dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damageEukaryotic DNA ligases: structural and functional insightsCombined immunodeficiency associated with DOCK8 mutationsStructural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joiningFunctional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joiningNovel susceptibility loci for second primary tumors/recurrence in head and neck cancer patients: large-scale evaluation of genetic variantsA human XRCC4-XLF complex bridges DNAXRCC4's interaction with XLF is required for coding (but not signal) end joiningXLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligationStructural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombinationRecruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domainATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cellDynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA endsDeletion of Ku70, Ku80, or both causes early aging without substantially increased cancerModes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4Modulation of DNA damage and repair pathways by human tumour virusesThe role of RecQ helicases in non-homologous end-joiningChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayDouble-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instabilityDiseases associated with defective responses to DNA damageDNA Damage and Pulmonary HypertensionCrystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJXRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break RepairNon-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactionsStructural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-JoiningStructural Insights into the Role of Domain Flexibility in Human DNA Ligase IV
P2860
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P248
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P2860
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@ast
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@en
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@en-gb
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@nl
type
label
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@ast
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@en
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@en-gb
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@nl
prefLabel
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@ast
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@en
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@en-gb
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining
@nl
P921
P3181
P1433
P1476
XLF interacts with the XRCC4-D ...... DNA nonhomologous end-joining.
@en
P2093
Peter Ahnesorg
Philippa Smith
P304
P3181
P356
10.1016/J.CELL.2005.12.031
P407
P577
2006-01-27T00:00:00Z