The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions. - Wikidata - wikimedia - TriplyDB

The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.

The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.

http://www.wikidata.org/entity/Q33707142

about

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair The RecQ DNA helicases in DNA repair Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA Molecular mechanism of resolving trinucleotide repeat hairpin by helicases Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding.Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1 Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast.Pif1 family helicases suppress genome instability at G-quadruplex motifs.Nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity.Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions.Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2 Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.Formation of complex and unstable chromosomal translocations in yeast DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.The roles of the Saccharomyces cerevisiae RecQ helicase SGS1 in meiotic genome surveillance.Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3.Telomeres: structures in need of unwinding.The dissolution of double Holliday junctions.Characterization of biochemical properties of Bacillus subtilis RecQ helicase Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes.RecQ helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection Holliday junction-containing DNA structures persist in cells lacking Sgs1 or Top3 following exposure to DNA damage.Top3-Rmi1 dissolve Rad51-mediated D loops by a topoisomerase-based mechanism.DNA2 drives processing and restart of reversed replication forks in human cells.The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication Overcoming natural replication barriers: differential helicase requirements.The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress.DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiae DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.The BLM dissolvasome in DNA replication and repair.H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.Dna2 is involved in CA strand resection and nascent lagging strand completion at native yeast telomeres.Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity.

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P2860

The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.

http://www.wikidata.org/entity/Q33707142

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The full-length Saccharomyces ...... ly unwinds holliday junctions.

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The full-length Saccharomyces ...... ly unwinds holliday junctions.

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type

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The full-length Saccharomyces ...... ly unwinds holliday junctions.

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The full-length Saccharomyces ...... ly unwinds holliday junctions.

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The full-length Saccharomyces ...... ly unwinds holliday junctions.

@ast

The full-length Saccharomyces ...... ly unwinds holliday junctions.

@en

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JBC.M109.083196

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Journal of Biological Chemistry

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The full-length Saccharomyces ...... ly unwinds holliday junctions.

@en

P2093

Petr Cejka

http://www.w3.org/2001/XMLSchema#string

Stephen C Kowalczykowski

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P2860

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Functional and physical interaction between WRN helicase and human replication protein A

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

The Bloom's syndrome gene product is homologous to RecQ helicases

Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli

The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA

The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins

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8290-8301

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scholarly article

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10.1074/JBC.M109.083196

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11

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285

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2010-01-19T00:00:00Z

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20086270

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Saccharomyces cerevisiae

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2832980

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