Germline variation controls the architecture of somatic alterations in tumors
about
Cancer pharmacogenomics: strategies and challengesEvaluation of allele-specific somatic changes of genome-wide association study susceptibility alleles in human colorectal cancersGenetic variants in the LEPR, CRY1, RNASEL, IL4, and ARVCF genes are prognostic markers of prostate cancer-specific mortality.Approaches to integrating germline and tumor genomic data in cancer research.Identity by descent mapping of founder mutations in cancer using high-resolution tumor SNP data.Exome sequencing reveals novel mutation targets in diffuse large B-cell lymphomas derived from Chinese patients.Applying microsatellite multiplex PCR analysis (MMPA) for determining allele copy-number status and percentage of normal cells within tumors.Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer.Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA.Germline copy number loss of UGT2B28 and gain of PLEC contribute to increased human esophageal squamous cell carcinoma risk in Southwest China.Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours.Inherited susceptibility to chronic lymphocytic leukemia: evidence and prospects for the future.Allele-specific imbalance mapping identifies HDAC9 as a candidate gene for cutaneous squamous cell carcinoma.Neurofibromatosis type 1-associated tumours: their somatic mutational spectrum and pathogenesis.The transcriptional regulatory network of proneural glioma determines the genetic alterations selected during tumor progression.Variants at the OCA2/HERC2 locus affect time to first cutaneous squamous cell carcinoma in solid organ transplant recipients collected using two different study designs.Allele-specific imbalance mapping at human orthologs of mouse susceptibility to colon cancer (Scc) loci.The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas.Is there a dose-dependent effect of genetic susceptibility loci for gastric cancer on prognosis of the patients?The pathogenesis of cutaneous squamous cell carcinoma in organ transplant recipients.Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes.Exome-wide analysis of bi-allelic alterations identifies a Lynch phenotype in The Cancer Genome Atlas
P2860
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P2860
Germline variation controls the architecture of somatic alterations in tumors
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Germline variation controls the architecture of somatic alterations in tumors
@ast
Germline variation controls the architecture of somatic alterations in tumors
@en
type
label
Germline variation controls the architecture of somatic alterations in tumors
@ast
Germline variation controls the architecture of somatic alterations in tumors
@en
prefLabel
Germline variation controls the architecture of somatic alterations in tumors
@ast
Germline variation controls the architecture of somatic alterations in tumors
@en
P2093
P2860
P1433
P1476
Germline variation controls the architecture of somatic alterations in tumors
@en
P2093
Amy M Dworkin
Boris C Bastian
Dawn C Allain
Dianne Bautista
Katie Ridd
O Hans Iwenofu
P2860
P304
P356
10.1371/JOURNAL.PGEN.1001136
P577
2010-09-23T00:00:00Z