Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation.

Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation.

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http://www.wikidata.org/entity/Q33718515
Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.Characterization of the C-Terminal Nuclease Domain of Herpes Simplex Virus pUL15 as a Target of Nucleotidyltransferase Inhibitors3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H.Pronounced Inhibition Shift from HIV Reverse Transcriptase to Herpetic DNA Polymerases by Increasing the Flexibility of α-Carboxy Nucleoside Phosphonates.Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral Activity.A 2-hydroxyisoquinoline-1,3-dione active site RNase H inhibitor binds in multiple modes to HIV-1 reverse transcriptase.Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities.Synthesis and biological assessment of 3,7-dihydroxytropolones.Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.Developing and evaluating inhibitors against the RNase H active site of HIV-1 RT.
P2860

Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation.

Item
http://www.wikidata.org/entity/Q33718515
description
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name
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@ast
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@en
type
label
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@ast
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@en
prefLabel
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@ast
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Inhibition of the ribonuclease ...... enzyme-inhibitor dissociation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932