Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting - Wikidata - wikimedia - TriplyDB

Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting

Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting

http://www.wikidata.org/entity/Q33724465

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The role of proopiomelanocortin (POMC) neurones in feeding behaviour Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene Developmental programming of hypothalamic neuronal circuits: impact on energy balance control SVA retrotransposons as potential modulators of neuropeptide gene expression Transcriptional Dynamics at Brain Enhancers: from Functional Specialization to Neurodegeneration Exaptation of transposable elements into novel cis-regulatory elements: is the evidence always strong?Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons Developmental specification of metabolic circuitry Mammalian comparative sequence analysis of the Agrp locus Genome-wide discovery of human heart enhancers.Expression of ankyrin repeat and suppressor of cytokine signaling box protein 4 (Asb-4) in proopiomelanocortin neurons of the arcuate nucleus of mice produces a hyperphagic, lean phenotype A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells.Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes beta-Endorphin expression in the mouse retina The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2 Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood Adult pituitary cell maintenance: lineage-specific contribution of self-duplication Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinning Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations.Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join them Obesity-programmed mice are rescued by early genetic intervention Molecular physiology of pituitary development: signaling and transcriptional networks.Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.Enhancer turnover and conserved regulatory function in vertebrate evolution.Transcription factors in the development of medial hypothalamic structures.Proopiomelanocortin expression in both GABA and glutamate neurons.Patterning, specification, and differentiation in the developing hypothalamus.Shared long-range regulatory elements coordinate expression of a gene cluster encoding nicotinic receptor heteromeric subtypes.Control of obesity and glucose intolerance via building neural stem cells in the hypothalamus.Hypothalamic-specific proopiomelanocortin deficiency reduces alcohol drinking in male and female mice.Tipping the scales early: probing the long-term effects of obesity.Evolution of transcriptional enhancers and animal diversity.17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior.Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity.Development of the Neuroendocrine Hypothalamus.Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake.

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Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting

http://www.wikidata.org/entity/Q33724465

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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Identification of neuronal enh ...... and phylogenetic footprinting

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Identification of neuronal enh ...... and phylogenetic footprinting

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Identification of neuronal enh ...... and phylogenetic footprinting

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Identification of neuronal enh ...... and phylogenetic footprinting

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Identification of neuronal enh ...... and phylogenetic footprinting

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Identification of neuronal enh ...... and phylogenetic footprinting

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Andrea M Santangelo

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Flávio S J de Souza

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James L Smart

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Malcolm J Low

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Marcelo Rubinstein

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María Elena Avale

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Viviana Bumaschny

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P2860

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

Analysis of vertebrate SCL loci identifies conserved enhancers

Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions

A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins

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