In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1
about
The molecular basis of HIV entryHuman Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus MacaquesAntigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cellsVaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2Cell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 EnvelopeFunctional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1)Recombinant expression, purification, and biophysical characterization of the transmembrane and membrane proximal domains of HIV-1 gp41.A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1.Multi-Parameter Exploration of HIV-1 Virus-Like Particles as Neutralizing Antibody Immunogens in Guinea Pigs, Rabbits and MacaquesAntibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralizationA low-molecular-weight entry inhibitor of both CCR5- and CXCR4-tropic strains of human immunodeficiency virus type 1 targets a novel site on gp41The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate.Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity.Increased functional stability and homogeneity of viral envelope spikes through directed evolution.Enzyme digests eliminate nonfunctional Env from HIV-1 particle surfaces, leaving native Env trimers intact and viral infectivity unaffected.Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding siteDynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infectionThe role of amino acid changes in the human immunodeficiency virus type 1 transmembrane domain in antibody binding and neutralizationBinding of anti-membrane-proximal gp41 monoclonal antibodies to CD4-liganded and -unliganded human immunodeficiency virus type 1 and simian immunodeficiency virus virionsImmunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.Discrete partitioning of HIV-1 Env forms revealed by viral capture.Assembly and characterization of gp160-nanodiscs: A new platform for biochemical characterization of HIV envelope spikes.Strategies for eliciting HIV-1 inhibitory antibodiesMolecular determinants of the ratio of inert to infectious virus particles.Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccineesNanoparticle-based flow virometry for the analysis of individual virionsAntigenic properties of the HIV envelope on virions in solution.A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV.Dense Array of Spikes on HIV-1 Virion Particles.HIV-1 virus-like particles bearing pure env trimers expose neutralizing epitopes but occlude nonneutralizing epitopes.In vitro assembly of a viral envelope.Rapid, quantitative mapping of anti-HIV type 1 envelope serum antibody specificities.Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at its Apex.Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle.Topological analysis of HIV-1 glycoproteins expressed in situ on virus surfaces reveals tighter packing but greater conformational flexibility than for soluble gp120.Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis.HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded.FUNCTIONAL OPTIMIZATION OF BROADLY NEUTRALIZING HIV-1 ANTIBODY 10E8 BY PROMOTING MEMBRANE INTERACTIONS.
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P2860
In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
In-solution virus capture assa ...... immunodeficiency virus type 1
@ast
In-solution virus capture assa ...... immunodeficiency virus type 1
@en
type
label
In-solution virus capture assa ...... immunodeficiency virus type 1
@ast
In-solution virus capture assa ...... immunodeficiency virus type 1
@en
prefLabel
In-solution virus capture assa ...... immunodeficiency virus type 1
@ast
In-solution virus capture assa ...... immunodeficiency virus type 1
@en
P2093
P2860
P356
P1433
P1476
In-solution virus capture assa ...... immunodeficiency virus type 1
@en
P2093
Daniel P Leaman
Heather Kinkead
Michael B Zwick
P2860
P304
P356
10.1128/JVI.02363-09
P577
2010-01-20T00:00:00Z