PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells. - Wikidata - wikimedia - TriplyDB

PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells.

PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells.

http://www.wikidata.org/entity/Q33727865

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GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease Inhibition of Phosphodiesterase 5 and Increasing the Level of Cyclic Guanosine 3',5' Monophosphate by Hydroalcoholic Achillea wilhelmsii C. Koch Extract in Human Breast Cancer Cell Lines MCF-7 and MDA-Mb-468.HSPA5/Dna K may be a useful target for human disease therapies.PDE5 inhibitors enhance celecoxib killing in multiple tumor types.PDE5 inhibitors as therapeutics for heart disease, diabetes and cancer Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95 OSU-03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-Brain Barrier: Implications for Anti-Cancer Therapies Nexavar/Stivarga and viagra interact to kill tumor cells.GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases.Celecoxib enhances [sorafenib + sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistance Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome.Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells.Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer.The role of cGMP and its signaling pathways in kidney disease.Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species.Potential synergistic effect of phosphodiesterase inhibitors with chemotherapy in lung cancer.Phosphodiesterase type 5 and cancers: progress and challenges.Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies.Repurposing drugs in oncology (ReDO)-selective PDE5 inhibitors as anti-cancer agents.Chemical modulation of autophagy as an adjunct to chemotherapy in childhood and adolescent brain tumors

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P2860

PDE5 inhibitors enhance the lethality of standard of care chemotherapy in pediatric CNS tumor cells.

http://www.wikidata.org/entity/Q33727865

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2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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PDE5 inhibitors enhance the le ...... in pediatric CNS tumor cells.

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PDE5 inhibitors enhance the le ...... in pediatric CNS tumor cells.

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PDE5 inhibitors enhance the le ...... in pediatric CNS tumor cells.

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PDE5 inhibitors enhance the le ...... in pediatric CNS tumor cells.

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PDE5 inhibitors enhance the le ...... in pediatric CNS tumor cells.

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Adam Conley

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Andrew Poklepovic

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Jane L Roberts

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Laurence Booth

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Mark Malkin

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Nichola Cruickshanks

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Rakesh C Kukreja

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Steven Grant

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P2860

PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

Sildenafil increases chemotherapeutic efficacy of doxorubicin in prostate cancer and ameliorates cardiac dysfunction.

Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis.

Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells.

The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease.

PDE5 inhibitors, sildenafil and vardenafil, reverse multidrug resistance by inhibiting the efflux function of multidrug resistance protein 7 (ATP-binding Cassette C10) transporter

Lapatinib and obatoclax kill breast cancer cells through reactive oxygen species-dependent endoplasmic reticulum stress.

Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.

Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells.

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10.4161/CBT.28553

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