Mitochondrial mutational spectra in human cells and tissues.
about
Keeping mtDNA in shape between generationsCalculating expected DNA remnants from ancient founding events in human population geneticsA critical reassessment of the role of mitochondria in tumorigenesisSomatic mutations in the mitochondria of rheumatoid arthritis synoviocytesModifiers of hearing impairment in humans and mice.High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples.Heteroduplexes in mixed-template amplifications: formation, consequence and elimination by 'reconditioning PCR'Mitochondrial correlation microscopy and nanolaser spectroscopy - new tools for biophotonic detection of cancer in single cells.The role of mitochondrial DNA mutations in mammalian agingA sensitive scanning technology for low frequency nuclear point mutations in human genomic DNA.Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity.Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues.Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms.8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stressMitochondrial DNA alterations in cancer.Mitochondrial DNA: impacting central and peripheral nervous systems.Ligation of high-melting-temperature 'clamp' sequence extends the scanning range of rare point-mutational analysis by constant denaturant capillary electrophoresis (CDCE) to most of the human genome.Dynamics of mitochondrial heteroplasmy in three families investigated via a repeatable re-sequencing study.Mitochondrial oxidative stress and mitochondrial DNA.Mitochondrial DNA mutations in the hematopoietic system.PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variationsSingle-molecule PCR: an artifact-free PCR approach for the analysis of somatic mutations.Mitochondrial DNA mutations in human colonic crypt stem cells.Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA.The approaches for manipulating mitochondrial proteomeScanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis.Cellular and population level processes influence the rate, accumulation and observed frequency of inherited and somatic mtDNA mutations.Analysis of mutational spectra by denaturing capillary electrophoresisNaked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age.Single molecule PCR in mtDNA mutational analysis: Genuine mutations vs. damage bypass-derived artifacts.Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism.Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism.Different characteristics of mitochondrial microsatellite instability between uterine leiomyomas and leiomyosarcomas.No microsatellite instability using Bethesda panel and revised markers in uterine leiomyomas.Numts help to reconstruct the demographic history of the ocellated lizard (Lacerta lepida) in a secondary contact zone.The Landscape of mtDNA Modifications in Cancer: A Tale of Two Cities.Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.Alternating terminal electron-acceptors at the basis of symbiogenesis: How oxygen ignited eukaryotic evolution.Mitochondrial mutations in acute leukaemia.
P2860
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P2860
Mitochondrial mutational spectra in human cells and tissues.
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Mitochondrial mutational spectra in human cells and tissues.
@ast
Mitochondrial mutational spectra in human cells and tissues.
@en
type
label
Mitochondrial mutational spectra in human cells and tissues.
@ast
Mitochondrial mutational spectra in human cells and tissues.
@en
prefLabel
Mitochondrial mutational spectra in human cells and tissues.
@ast
Mitochondrial mutational spectra in human cells and tissues.
@en
P2093
P2860
P356
P1476
Mitochondrial mutational spectra in human cells and tissues.
@en
P2093
P2860
P304
13798-13803
P356
10.1073/PNAS.94.25.13798
P407
P577
1997-12-01T00:00:00Z