Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver.
about
Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cellsHepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretionOverexpression of the tumor autocrine motility factor receptor Gp78, a ubiquitin protein ligase, results in increased ubiquitinylation and decreased secretion of apolipoprotein B100 in HepG2 cellsNascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin BMicrosomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidationMicrosomal triglyceride transfer protein and its role in apoB-lipoprotein assemblyStructure of the Sec23p/24p and Sec13p/31p complexes of COPIIStimulation of the in vivo production of very low density lipoproteins by apolipoprotein E is independent of the presence of the low density lipoprotein receptor.Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia.A novel potential biomarker for metabolic syndrome in Chinese adults: Circulating protein disulfide isomerase family A, member 4.Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion.Apolipoprotein B-containing lipoprotein assembly in microsomal triglyceride transfer protein-deficient McA-RH7777 cells.Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein BNiacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells.Clinical and preclinical pharmacokinetics and pharmacodynamics of mipomersen (kynamro(®)): a second-generation antisense oligonucleotide inhibitor of apolipoprotein BMechanisms involved in the selective transfer of long chain polyunsaturated Fatty acids to the fetus.Lipid transport in cholecystokinin knockout mice.MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesisIncreased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β.Metabolic syndrome: focus on dyslipidemia.Effects of pyrazole partial agonists on HCA(2) -mediated flushing and VLDL-triglyceride levels in mice.Lipoprotein metabolism in chronic renal insufficiency.The physiological and molecular regulation of lipoprotein assembly and secretion.High-carbohydrate diets affect the size and composition of plasma lipoproteins in hamsters (Mesocricetus auratus).Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients.Niacin: an old drug rejuvenated.Mipomersen (kynamro): a novel antisense oligonucleotide inhibitor for the management of homozygous familial hypercholesterolemia.New therapies targeting apoB metabolism for high-risk patients with inherited dyslipidaemias: what can the clinician expect?Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB.Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein.Inhibition of microsomal triglyceride transfer protein expression and atherogenic risk factor apolipoprotein B100 secretion by tanshinone IIA in HepG2 cells.Proteomic and lipid characterization of apolipoprotein B-free luminal lipid droplets from mouse liver microsomes: implications for very low density lipoprotein assembly.Aluminum-induced mitochondrial dysfunction leads to lipid accumulation in human hepatocytes: a link to obesity.Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells.Cytoplasmic lipid droplets are sites of convergence of proteasomal and autophagic degradation of apolipoprotein B.Amino acid sequences within the beta1 domain of human apolipoprotein B can mediate rapid intracellular degradation.A role for palmitoylation in the quality control, assembly and secretion of apolipoprotein BContribution of HDL-apolipoproteins to the inhibition of low density lipoprotein oxidation and lipid accumulation in macrophages.Overexpression of apolipoprotein A-IV enhances lipid transport in newborn swine intestinal epithelial cells.Apolipoprotein B is synthesized in selected human non-hepatic cell lines but not processed into mature lipoprotein.
P2860
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P2860
Cell and molecular biology of the assembly and secretion of apolipoprotein B-containing lipoproteins by the liver.
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cell and molecular biology of ...... ing lipoproteins by the liver.
@ast
Cell and molecular biology of ...... ing lipoproteins by the liver.
@en
type
label
Cell and molecular biology of ...... ing lipoproteins by the liver.
@ast
Cell and molecular biology of ...... ing lipoproteins by the liver.
@en
prefLabel
Cell and molecular biology of ...... ing lipoproteins by the liver.
@ast
Cell and molecular biology of ...... ing lipoproteins by the liver.
@en
P1476
Cell and molecular biology of ...... ing lipoproteins by the liver.
@en
P2093
P356
10.1016/S1388-1981(99)00083-9
P407
P577
1999-08-01T00:00:00Z