Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. - Wikidata - wikimedia - TriplyDB

Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.

Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.

http://www.wikidata.org/entity/Q33733198

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Preclinical evidences toward the use of triterpenoid CDDO-Me for solid cancer prevention and treatment New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards Myeloid-Derived Suppressor Cells in Bacterial Infections Cancer-Associated Myeloid Regulatory Cells Hampering immune suppressors: therapeutic targeting of myeloid-derived suppressor cells in cancer From tumor immunosuppression to eradication: targeting homing and activity of immune effector cells to tumors Broad targeting of angiogenesis for cancer prevention and therapy Myeloid-derived suppressor cells as therapeutic target in hematological malignancies Rationale for a Multimodality Strategy to Enhance the Efficacy of Dendritic Cell-Based Cancer Immunotherapy.Targeting Immune Regulatory Networks to Counteract Immune Suppression in Cancer Pro-Tumoral Inflammatory Myeloid Cells as Emerging Therapeutic Targets Signal transducer and activator of transcription 3 in myeloid-derived suppressor cells: an opportunity for cancer therapy Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents Myeloid-derived cells are key targets of tumor immunotherapy Molecular pathways: inflammation-associated nitric-oxide production as a cancer-supporting redox mechanism and a potential therapeutic target Modification of the tumor microenvironment as a novel target of renal cell carcinoma therapeutics Coordinated regulation of myeloid cells by tumours The emerging immunological role of post-translational modifications by reactive nitrogen species in cancer microenvironment Macrophage Migration Inhibitory Factor as an Emerging Drug Target to Regulate Antioxidant Response Element System Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy Myeloid derived suppressor cells - a new therapeutic target in the treatment of cancer.Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy.The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists.NRF2, cancer and calorie restriction HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.Comparative expression profiling of distinct T cell subsets undergoing oxidative stress.Bardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.Role of immune-regulatory cells in skin pathology.Effect of TLR agonists on the differentiation and function of human monocytic myeloid-derived suppressor cells Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study.Increased level of myeloid-derived suppressor cells, programmed death receptor ligand 1/programmed death receptor 1, and soluble CD25 in Sokal high risk chronic myeloid leukemia Radiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound.Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction Molecular pathways: myeloid complicity in cancer.Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions.

P2860

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P2860

Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.

http://www.wikidata.org/entity/Q33733198

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Anti-inflammatory triterpenoid ...... ves immune response in cancer.

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Anti-inflammatory triterpenoid ...... ves immune response in cancer.

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type

label

Anti-inflammatory triterpenoid ...... ves immune response in cancer.

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Anti-inflammatory triterpenoid ...... ves immune response in cancer.

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Anti-inflammatory triterpenoid ...... ves immune response in cancer.

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Anti-inflammatory triterpenoid ...... ves immune response in cancer.

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1078-0432.CCR-09-3272

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Clinical Cancer Research

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Anti-inflammatory triterpenoid ...... oves immune response in cancer

@en

P2093

Bhupendra Rawal

http://www.w3.org/2001/XMLSchema#string

Carlos R Becerra

http://www.w3.org/2001/XMLSchema#string

Colin Meyer

http://www.w3.org/2001/XMLSchema#string

Cristina Iclozan

http://www.w3.org/2001/XMLSchema#string

Dmitry I Gabrilovich

http://www.w3.org/2001/XMLSchema#string

Hannah Weber

http://www.w3.org/2001/XMLSchema#string

Je-In Youn

http://www.w3.org/2001/XMLSchema#string

Ji-Hyun Lee

http://www.w3.org/2001/XMLSchema#string

Lily Lu

http://www.w3.org/2001/XMLSchema#string

Matthew J Cotter

http://www.w3.org/2001/XMLSchema#string

P2860

Myeloid-derived suppressor cells: linking inflammation and cancer

Myeloid-derived suppressor cells as regulators of the immune system

Suppression of proximal T cell receptor signaling and lytic function in CD8+ tumor-infiltrating T cells

Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells.

Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells.

CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells.

Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination

Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species.

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway

Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3

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1812-1823

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scholarly article

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10.1158/1078-0432.CCR-09-3272

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6

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16

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2010-03-09T00:00:00Z

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20215551

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2840181

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