Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.
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Treg cells: a potential regulator for IL-22 expression?Regulatory T cells in autoimmune neuroinflammationAlong the Axis between Type 1 and Type 2 Immunity; Principles Conserved in Evolution from Fish to MammalsIntegrating signals from the T-cell receptor and the interleukin-2 receptorStochastic responses may allow genetically diverse cell populations to optimize performance with simpler signaling networksAn anti-interleukin-2 receptor drug attenuates T- helper 1 lymphocytes-mediated inflammation in an acute model of endotoxin-induced uveitisThe effects of interleukin-2 on immune response regulation.Polyfunctional responses by human T cells result from sequential release of cytokines.Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data.FoxP3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability.Low-dose interleukin-2 promotes STAT-5 phosphorylation, Treg survival and CTLA-4-dependent function in autoimmune liver diseasesThe type of responder T-cell has a significant impact in a human in vitro suppression assay.Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy.Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback.Anti-CD40-mediated cancer immunotherapy: an update of recent and ongoing clinical trials.CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model.IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.Social interaction in synthetic and natural microbial communities.Using an adaptive gene network model for self-organizing multicellular behavior.Systems biology in immunology: a computational modeling perspective.Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction.Three-Dimensional Gradients of Cytokine Signaling between T Cells.Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.PDE/ODE modeling and simulation to determine the role of diffusion in long-term and -range cellular signaling.Timescales of IP(3)-evoked Ca(2+) spikes emerge from Ca(2+) puffs only at the cellular levelT Cells Integrate Local and Global Cues to Discriminate between Structurally Similar AntigensThe molecular mechanisms of regulatory T cell immunosuppressionQuorum-Sensing in CD4(+) T Cell Homeostasis: A Hypothesis and a Model.Design principles of cell circuits with paradoxical components.Continuum model of T-cell avidity: Understanding autoreactive and regulatory T-cell responses in type 1 diabetes.The Role of Regulatory T Cells in Mesothelioma.Optimization and qualification of a multiplex bead array to assess cytokine and chemokine production by vaccine-specific cells.Regulatory T Cells in Melanoma Revisited by a Computational Clustering of FOXP3+ T Cell Subpopulations.Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapyQuorum sensing allows T cells to discriminate between self and nonselfEngineering nano- and microparticles to tune immunitySynergistic Communication between CD4+ T Cells and Monocytes Impacts the Cytokine Environment.An essential role for the IL-2 receptor in Treg cell function.Myeloid and T Cell-Derived TNF Protects against Central Nervous System Tuberculosis.T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.
P2860
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P2860
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Competing feedback loops shape ...... in cellular microenvironments.
@ast
Competing feedback loops shape ...... in cellular microenvironments.
@en
type
label
Competing feedback loops shape ...... in cellular microenvironments.
@ast
Competing feedback loops shape ...... in cellular microenvironments.
@en
prefLabel
Competing feedback loops shape ...... in cellular microenvironments.
@ast
Competing feedback loops shape ...... in cellular microenvironments.
@en
P2093
P2860
P356
P1476
Competing feedback loops shape ...... in cellular microenvironments
@en
P2093
Dorothea Busse
Kevin Thurley
Kirstin Hobiger
Maurus de la Rosa
Michael Flossdorf
P2860
P304
P356
10.1073/PNAS.0812851107
P407
P577
2010-01-28T00:00:00Z