Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.
about
Control of the thymic medulla and its influence on αβT-cell developmentCellular and molecular regulation of innate inflammatory responsesγδ T Cell-Dependent Regulatory T Cells Prevent the Development of Autoimmune Keratitis.Targeting Treg signaling for the treatment of autoimmune diseasesUnbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD.CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T CellsIncreased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.Low-dose IL-2 selectively activates subsets of CD4+ Tregs and NK cells.Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress.RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T CellsT-cell selection in the thymus: a spatial and temporal perspective.Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen.How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity.Cell death and thymic tolerance.IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes.The multiple pathways to autoimmunity.Rapamycin results in Bim-mediated loss of thymic regulatory T cells during development in organ culture.IL-2 prevents deletion of developing T-regulatory cells in the thymus.Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.CCR7 Modulates the Generation of Thymic Regulatory T Cells by Altering the Composition of the Thymic Dendritic Cell Compartment.IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells.Preparation and Applications of Organotypic Thymic Slice Cultures.Altered homeostasis and development of regulatory T cell subsets represent an IL-2R-dependent risk for diabetes in NOD mice.Thymic function in the regulation of T cells, and molecular mechanisms underlying the modulation of cytokines and stress signaling (Review).Chemokine-Mediated Choreography of Thymocyte Development and Selection.Low doses of IgG from atopic individuals can modulate in vitro IFN-γ production by human intra-thymic TCD4 and TCD8 cells: An IVIg comparative approach.Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity.
P2860
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P2860
Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Thymic regulatory T cell niche ...... ells and feedback competition.
@ast
Thymic regulatory T cell niche ...... ells and feedback competition.
@en
type
label
Thymic regulatory T cell niche ...... ells and feedback competition.
@ast
Thymic regulatory T cell niche ...... ells and feedback competition.
@en
prefLabel
Thymic regulatory T cell niche ...... ells and feedback competition.
@ast
Thymic regulatory T cell niche ...... ells and feedback competition.
@en
P2093
P2860
P356
P1433
P1476
Thymic regulatory T cell niche ...... ells and feedback competition.
@en
P2093
Brian M Weist
Ellen A Robey
Jeremy Boussier
Nadia Kurd
Shiao Wei Chan
P2860
P2888
P304
P356
10.1038/NI.3171
P407
P577
2015-05-04T00:00:00Z
P5875
P6179
1017118348