Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B - Wikidata - wikimedia - TriplyDB

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

http://www.wikidata.org/entity/Q33741869

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Transcriptome Analysis in Domesticated Species: Challenges and Strategies Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies Comparative oncology: what dogs and other species can teach us about humans with cancer Canine cancer immunotherapy studies: linking mouse and human.GWAS is going to the dogs.Insights into morphology and disease from the dog genome project.Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.A New Paradigm to Mitigate Osteosarcoma by Regulation of MicroRNAs and Suppression of the NF-κB Signaling Cascade.Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency.A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test.Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background Genome-Wide Analysis Identifies Germ-Line Risk Factors Associated with Canine Mammary Tumours.Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci.Comparative genomics of canine hemoglobin genes reveals primacy of beta subunit delta in adult carnivores.Aberrant Retinoblastoma (RB)-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma.Genome-wide association analysis in dogs implicates 99 loci as risk variants for anterior cruciate ligament rupture.A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity.Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.Association of common variants in MTAP with susceptibility and overall survival of osteosarcoma: a two-stage population-based study in Han Chinese.Osteosarcoma inheritance in two families of Scottish deerhounds.Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness.Naturally occurring cancers in dogs: insights for translational genetics and medicine.Canine osteosarcoma: a naturally occurring disease to inform pediatric oncology.Germline gene polymorphisms predisposing domestic mammals to carcinogenesis.The canine era: the rise of a biomedical model.Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder.Molecular genetics of osteosarcoma.Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics.Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma.Comparative Aspects of Osteosarcoma Pathogenesis in Humans and Dogs.Demographic history, selection and functional diversity of the canine genome.Understanding the Osteosarcoma Pathobiology: A Comparative Oncology Approach.Advances in the Treatment of Pediatric Bone Sarcomas.Canine NAPEPLD-associated models of human myelin disorders.A Bayesian Gene-Based Genome-Wide Association Study Analysis of Osteosarcoma Trio Data Using a Hierarchically Structured Prior.Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53

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Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

http://www.wikidata.org/entity/Q33741869

description

2013 nî lūn-bûn

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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Genome-wide analyses implicate ...... ulatory variants near CDKN2A/B

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Genome-wide analyses implicate ...... ulatory variants near CDKN2A/B

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Identification of Differentially Expressed MicroRNAs in Osteosarcoma

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

An integrated encyclopedia of DNA elements in the human genome

A high-resolution map of human evolutionary constraint using 29 mammals

Genome sequence, comparative analysis and haplotype structure of the domestic dog

Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis

Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells

NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The accessible chromatin landscape of the human genome

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