about
Genome sequence, comparative analysis and haplotype structure of the domestic dogA high-resolution comparative map of canine Chromosome 5q14.3-q33 constructed utilizing the 1.5x canine genome sequence.Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/BFLT3 mutations in canine acute lymphocytic leukemiaA genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis.Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcomaOrigins and evolution of a transmissible cancer.The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplificationCanine prostate cancer cell line (Probasco) produces osteoblastic metastases in vivo'Putting our heads together': insights into genomic conservation between human and canine intracranial tumorsAlterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics.A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity.Chromosome aberrations in canine multicentric lymphomas detected with comparative genomic hybridisation and a panel of single locus probesThe application of FISH techniques for physical mapping in the dog (Canis familiaris).Generation and characterization of novel canine malignant mast cell line CL1.Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL.Physical and linkage mapping of the canine phosphate carrier (SLC25A3) and apoptotic activating factor 1 (APAF1) genes to canine chromosome 15.Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes.Comparative genomic hybridization (CGH) in dogs--application to the study of a canine glial tumour cell line.Molecular cytogenetic analysis of a novel high-grade canine T-lymphoblastic lymphoma demonstrating co-expression of CD3 and CD79a cell markers.Zoo-FISH analysis of dog chromosome 5: identification of conserved synteny with human and cat chromosomes.Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog (Canis familiaris) and human.FISH mapping and identification of canine chromosomes.Reading between the lines: molecular characterization of five widely used canine lymphoid tumour cell lines.Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma.Chromosome-specific single-locus FISH probes allow anchorage of an 1800-marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes.Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade.IDH1 and IDH2 hotspot mutations are not found in canine glioma.Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas.Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart.Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma.A cytogenetically characterized, genome-anchored 10-Mb BAC set and CGH array for the domestic dog.Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine.Canine Histiocytic Malignancies-Challenges and Opportunities.The Establishment of the Pfizer-Canine Comparative Oncology and Genomics Consortium Biospecimen Repository.Cytogenomics of Feline Cancers: Advances and Opportunities.Extensive conservation of genomic imbalances in canine transmissible venereal tumors (CTVT) detected by microarray-based CGH analysis.A canine cancer-gene microarray for CGH analysis of tumors.Evaluation of gene expression and DNA copy number profiles of adipose tissue-derived stromal cells and consecutive neurosphere-like cells generated from dogs with naturally occurring spinal cord injury.Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma
P50
Q22122465-E61720FF-7AC6-4A1A-BE2D-56E55DA506D4Q31111955-48D2925A-83A7-44C7-9703-ABA889F96D14Q33741869-49DF1793-5D69-4E21-9E9B-BBB53E5EFA68Q33805426-1CC85405-415E-458B-97D0-09CC1A15E646Q33869673-41A14B0D-76C9-4AF9-AB9E-B9C103E5D1ACQ33919862-CE28C403-80D5-4933-B492-790C9BE64AE6Q34017584-54B8E10F-3AF4-4C13-9AB2-1FAA90B39082Q34181123-0409DB0A-C4D5-4598-9E3D-F6695F07CFF6Q34438300-AA3E355F-59AF-49D4-9BDA-FB3F0971785FQ35575628-C4AA5F61-D2AF-49EF-B32F-EEF7B8780E34Q36210054-D4A8FFC0-8D70-42B2-A7FE-23E26249B1FEQ36339140-561BD8FE-7D42-42E6-A130-E6B4C2978450Q36671265-33E05027-A072-4A9A-BB0C-2576A7176DE4Q36830848-D5AFC1B5-7488-4061-8F6B-BF325FC95269Q37095268-8DAA11B2-1F8D-44EB-B3D3-4A16FE336B6BQ37126996-707B0AAC-2615-47FE-A060-0F0838FF3951Q38299671-80C2251A-03BD-4F0A-9DB4-8B25821B6BD4Q38436890-3141B85D-53FD-4E32-9E67-0473A2331151Q38464136-767F7500-1FCB-4962-A9E7-F60A371C6A59Q38490880-3239FBC8-570D-4353-870D-10EF4B1626B0Q38498112-8A8A66F5-16FC-4EBF-8E23-31A6C197FA97Q38498912-3BF11834-D318-4A8B-A405-291A0DCF2965Q38500928-DF107635-B5E6-4A34-AD6B-5A59E7C9D53AQ39413798-2018C72C-0908-48FB-85B6-0320BDD824A7Q40376614-B1EB1FE1-E8CF-401A-B626-ACEF7B939A22Q40415431-AD15D105-DBFC-471D-A228-EDBC95074927Q40433142-0D66F63B-EABF-4622-800B-D54EB382BDF7Q41137508-1113B8EF-AE4D-41CA-9111-09E5F5A0E9B2Q44856242-559931B9-6EFD-403E-A1E7-206E64FE7361Q44861620-BB5DD43E-F0A8-4DB3-9242-2EC1EE26363FQ44863958-EDC1D8D7-AD19-4124-BEF4-8E903323D894Q44871244-1B9CACBA-3963-4C16-92E4-169504D8EFF9Q44871247-6C7E7354-11F1-4D13-9C18-2CD0CB7D576FQ44876356-2540A692-45BB-4789-817F-2ACE55C8EC78Q44876407-750DEAAA-7632-48F4-9E96-A00CDF1B4E30Q44876420-181E1002-59C1-4940-9524-A5329D9E5779Q44878217-864AB2E7-3815-4F50-A73D-CAEB9A0D7CCBQ47199804-9E96369E-0E52-4FFA-A0E4-DD1FA43553EEQ47325493-5779EF78-A0C3-4981-B749-59ACA6102FDEQ80557198-F1006241-4720-41A9-8701-F54F28EA4763
P50
description
researcher ORCID ID = 0000-0002-3029-8798
@en
wetenschapper
@nl
name
Rachael Thomas
@ast
Rachael Thomas
@en
Rachael Thomas
@es
Rachael Thomas
@nl
type
label
Rachael Thomas
@ast
Rachael Thomas
@en
Rachael Thomas
@es
Rachael Thomas
@nl
prefLabel
Rachael Thomas
@ast
Rachael Thomas
@en
Rachael Thomas
@es
Rachael Thomas
@nl
P106
P31
P496
0000-0002-3029-8798