Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy.
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Low dose versus high dose stavudine for treating people with HIV infectionLow dose versus high dose stavudine for treating people with HIV infectionThe role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implicationsStatin adverse effects : a review of the literature and evidence for a mitochondrial mechanismMitochondrial DNA haplogroups influence AIDS progressionBench-to-bedside review: severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitorsAntiviral activities and cellular toxicities of modified 2',3'-dideoxy-2',3'-didehydrocytidine analogues.Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial ToxicityThe kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogsC elegans: a model for exploring the genetics of fat storageEffects of gas and other fume emitting heaters on the development of asthma during childhoodBody composition changes in protease inhibitor-naive HIV-infected patients treated with two nucleoside reverse transcriptase inhibitors.Phosphorylation of nucleoside analog antiretrovirals: a review for clinicians.Toxicities associated with dual nucleoside reverse-transcriptase inhibitor regimens in HIV-infected children.Mitochondrial DNA depletion and respiratory chain activity in primary human subcutaneous adipocytes treated with nucleoside analogue reverse transcriptase inhibitorsMetabolic complications of in utero maternal HIV and antiretroviral exposure in HIV-exposed infantsAntiretroviral therapy-induced mitochondrial toxicity: potential mechanisms beyond polymerase-γ inhibition.HIV-associated lipodystrophy syndrome.Procedure, applications, and outcomes of autologous fat grafting.Manipulating the Mitochondrial Genome To Enhance Cattle Embryo Development.Clinical factors associated with plasma F2-isoprostane levels in HIV-infected adults.Structured antiretroviral treatment interruptions in chronically HIV-1-infected subjects.Coronary artery disease and human immunodeficiency virus infection.Disorders of glucose metabolism in patients infected with human immunodeficiency virus.Mitochondrial toxicity and HIV therapy.Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging.Zidovudine induces downregulation of mitochondrial deoxynucleoside kinases: implications for mitochondrial toxicity of antiviral nucleoside analogs.NRTI induced mitochondrial toxicity as a mechanism for HAART related lipodystrophy: fact or fiction?HIV-associated lipodystrophy.Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?Strategies for treating HIV-related lipodystrophy.Nutrition and HIV infection.Intracellular drug concentrations.Association of thymidylate synthase polymorphisms with acute pancreatitis and/or peripheral neuropathy in HIV-infected patients on stavudine-based therapyRecombinant human growth hormone and rosiglitazone for abdominal fat accumulation in HIV-infected patients with insulin resistance: a randomized, double-blind, placebo-controlled, factorial trialThe evaluation of metabolic function and fat redistribution in clinical trials.Pathology of the breast associated with HIV/AIDS.Evaluation and management of dyslipidemia in patients with HIV infection.No longitudinal mitochondrial DNA sequence changes in HIV-infected individuals with and without lipoatrophy.
P2860
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P2860
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@ast
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@en
type
label
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@ast
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@en
prefLabel
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@ast
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@en
P2093
P1433
P1476
Mitochondrial toxicity induced ...... therapy-related lipodystrophy.
@en
P2093
J A Romijn
J A Smeitink
K Brinkman
P304
P356
10.1016/S0140-6736(99)06102-4
P407
P577
1999-09-01T00:00:00Z