The kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogs
about
Oxidative stress induced S-glutathionylation and proteolytic degradation of mitochondrial thymidine kinase 2Zidovudine induces downregulation of mitochondrial deoxynucleoside kinases: implications for mitochondrial toxicity of antiviral nucleoside analogs.Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathwaysBalancing antiviral potency and host toxicity: identifying a nucleotide inhibitor with an optimal kinetic phenotype for HIV-1 reverse transcriptase.Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondriaThymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation.Mitochondrial purine and pyrimidine metabolism and beyond.Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity.
P2860
Q34278809-6D7E9640-1FC9-4A99-951A-2B7659461DF8Q34436535-676F1D81-CE94-4CA9-AC5A-A3611E5C93E8Q35219161-640907CA-A4FC-4381-85A1-BB31DA6C9139Q36057386-53F20370-1023-49C7-AFCE-BB16133B39C5Q36060187-C5267E39-54FA-432F-A3C8-0FB09B7FF659Q37054681-918ED227-03B6-44ED-AE00-220D4841D453Q39025697-82351656-B279-4C92-8AE4-5C3E0C60722BQ44797235-E156F605-14FC-440D-8F60-87FAB44E1985
P2860
The kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogs
description
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Juni 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/06/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/06/01)
@nl
наукова стаття, опублікована в червні 2011
@uk
مقالة علمية (نشرت في يونيو 2011)
@ar
name
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@ast
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@en
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@nl
type
label
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@ast
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@en
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@nl
prefLabel
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@ast
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@en
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@nl
P2093
P2860
P356
P1476
The kinetic effects on thymidi ...... of antiviral thymidine analogs
@en
P2093
Staffan Eriksson
P2860
P304
P356
10.1128/AAC.00109-11
P407
P577
2011-06-01T00:00:00Z