Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function
about
OIT3 deficiency impairs uric acid reabsorption in renal tubuleCommon noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expressionDevelopment of next generation sequencing panel for UMOD and association with kidney disease.A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress.Common variants in UMOD associate with urinary uromodulin levels: a meta-analysisThe glycolytic enzymes glyceraldehyde 3-phosphate dehydrogenase and enolase interact with the renal epithelial K+ channel ROMK2 and regulate its function.Regulation of potassium channel trafficking in the distal nephron.Thick ascending limb of the loop of Henle.Characterization of a recurrent in-frame UMOD indel mutation causing late-onset autosomal dominant end-stage renal failureUromodulin in kidney injury: an instigator, bystander, or protector?Genome-wide association studies and contribution to cardiovascular physiologyA single nucleotide polymorphism in the UMOD promoter is associated with end stage renal diseaseAssociations of Urinary Uromodulin with Clinical Characteristics and Markers of Tubular Function in the General Population.Clinical, Genetic, and Urinary Factors Associated with Uromodulin ExcretionThe serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levelsUromodulin upregulates TRPV5 by impairing caveolin-mediated endocytosis.Scraping fibrosis: UMODulating renal fibrosis.Uromodulin: old friend with new roles in health and disease.Mitochondrial channels: ion fluxes and more.The signaling pathway of uromodulin and its role in kidney diseases.Uromodulin: from monogenic to multifactorial diseases.Uromodulin: from physiology to rare and complex kidney disorders.Activation of the bumetanide-sensitive Na+,K+,2Cl- cotransporter (NKCC2) is facilitated by Tamm-Horsfall protein in a chloride-sensitive mannerRole of renal transporters and novel regulatory interactions in the TAL that control blood pressure.Uromodulin gene variants and their association with renal function and blood pressure in cats: a pilot study.The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution.Determination of uromodulin in human urine: influence of storage and processing.A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia.Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis.Tamm-Horsfall Protein/Uromodulin Deficiency Elicits Tubular Compensatory Responses Leading to Hypertension and Hyperuricemia.Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy.The importance of uromodulin as regulator of salt reabsorption along the thick ascending limb
P2860
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P2860
Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@ast
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@en
type
label
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@ast
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@en
prefLabel
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@ast
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@en
P2093
P2860
P356
P1476
Tamm-Horsfall glycoprotein int ...... MK2 and regulates its function
@en
P2093
Aparna Renigunta
Kerim Mutig
Niels Decher
Siegfried Waldegger
Turgay Saritas
Vijay Renigunta
P2860
P304
P356
10.1074/JBC.M110.149880
P407
P577
2010-11-16T00:00:00Z