about
Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleedingCentral role of the P2Y12 receptor in platelet activationPlatelet inhibition with prasugrel (CS-747) compared with clopidogrel in patients undergoing coronary stenting: the subset from the JUMBO studyP2Y12 receptors: structure and functionImpaired activation of murine platelets lacking G alpha(i2)The C6-2B glioma cell P2Y(AC) receptor is pharmacologically and molecularly identical to the platelet P2Y(12) receptorADP and platelets: the end of the beginningMolecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugsMore pieces of the platelet activation puzzle slide into placeInherited platelet-based bleeding disorders.Congenital platelet disorders and understanding of platelet function.The creation of an antithrombotic surface by apyrase immobilizationA natural dominant negative P2X1 receptor due to deletion of a single amino acid residue.Constitutively released adenosine diphosphate regulates proplatelet formation by human megakaryocytes.Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor.Historical perspective and future directions in platelet research.Clopidogrel: interactions with the P2Y12 receptor and clinical relevance.Characterization of the cytokine profile of platelet rich plasma (PRP) and PRP-induced cell proliferation and migration: Upregulation of matrix metalloproteinase-1 and -9 in HaCaT cells(N)-methanocarba-2MeSADP (MRS2365) is a subtype-specific agonist that induces rapid desensitization of the P2Y1 receptor of human platelets.Induction of novel agonist selectivity for the ADP-activated P2Y1 receptor versus the ADP-activated P2Y12 and P2Y13 receptors by conformational constraint of an ADP analog.Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coatingPlatelets, arterial thrombosis and cerebral ischemia.Platelet signaling-a primer.An overview of phenylcyclopropylamine derivatives: biochemical and biological significance and recent developments.P2Y12 receptor: platelet thrombus formation and medical interventions.Harnessing the platelet signaling network to produce an optimal hemostatic response.The role of P2Y₁₂ receptor and activated platelets during inflammation.Molecular defects of the platelet P2 receptors.Similar Impact of Clopidogrel or Ticagrelor on Carotid Atherosclerotic Plaque Inflammation.Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders.New Concepts and Mechanisms of Platelet Activation Signaling.Adenine triphosphate nucleotides are antagonists at the P2Y receptor.Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets.G-protein-gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases.Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets.Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation.The P2Y(12) receptor induces platelet aggregation through weak activation of the alpha(IIb)beta(3) integrin--a phosphoinositide 3-kinase-dependent mechanism.Patients with congenital abnormality of platelet aggregation induced by Ca(2+) ionophores may have a defect of the platelet P2Y(12) receptor for ADP.A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets.Small aggregates of platelets can be detected sensitively by a flow cytometer equipped with an imaging device: mechanisms of epinephrine-induced aggregation and antiplatelet effects of beraprost.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
ADP receptors and clinical bleeding disorders.
@ast
ADP receptors and clinical bleeding disorders.
@en
type
label
ADP receptors and clinical bleeding disorders.
@ast
ADP receptors and clinical bleeding disorders.
@en
prefLabel
ADP receptors and clinical bleeding disorders.
@ast
ADP receptors and clinical bleeding disorders.
@en
P1476
ADP receptors and clinical bleeding disorders.
@en
P2093
P304
P356
10.1161/01.ATV.19.10.2281
P407
P577
1999-10-01T00:00:00Z