Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets.
about
Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human plateletsP2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activationHematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation.Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.Lyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretionG(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets.Protein kinase C ε expression in platelets from patients with acute myocardial infarction.PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation.Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311.Protein kinase Cδ mediates the activation of protein kinase D2 in plateletsNew insights into protease-activated receptor 4 signaling pathways in the pathogenesis of inflammation and neuropathic pain: a literature reviewOxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BIPrimary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation.IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosisDistinct role of Pyk2 in mediating thromboxane generation downstream of both G12/13 and integrin αIIbβ3 in plateletsImpaired activation of platelets lacking protein kinase C-theta isoformQuantitative time-resolved phosphoproteomic analysis of mast cell signaling.Protein kinase C[delta] differentially regulates platelet functional responses.Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.Proteomic profiling of platelet signalling.Src family kinases: at the forefront of platelet activationCoincident regulation of PKCdelta in human platelets by phosphorylation of Tyr311 and Tyr565 and phospholipase C signallingRegulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets.G-protein-gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases.Platelet free cytosolic calcium concentration during ageing of type 2 diabetic patients.Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.Trypsin causes platelet activation independently of known protease-activated receptors.
P2860
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P2860
Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@en
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@nl
type
label
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@en
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@nl
prefLabel
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@en
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@nl
P2093
P2860
P1433
P1476
Molecular mechanism and functi ...... tion of PKCdelta in platelets.
@en
P2093
Haripriya Shankar
Jianguo Jin
Robert T Dorsam
Satya P Kunapuli
Surya Bhamidipati
Swaminathan Murugappan
P2860
P304
P356
10.1182/BLOOD-2004-12-4866
P407
P577
2005-04-05T00:00:00Z