Inferences about the distribution of dominance drawn from yeast gene knockout data.
about
Weak selection and protein evolutionCan the experimental evolution programme help us elucidate the genetic basis of adaptation in nature?Evidence for increased levels of positive and negative selection on the X chromosome versus autosomes in humans.The high-throughput yeast deletion fitness data and the theories of dominance.The consequences of rare sexual reproduction by means of selfing in an otherwise clonally reproducing species.Properties and modeling of GWAS when complex disease risk is due to non-complementing, deleterious mutations in genes of large effect.Sex-differential selection and the evolution of X inactivation strategiesMasculinization of the x chromosome in the pea aphid.Loss-of-heterozygosity facilitates passage through Haldane's sieve for Saccharomyces cerevisiae undergoing adaptation.Fitness landscapes: an alternative theory for the dominance of mutationDominance genetic variance for traits under directional selection in Drosophila serrata.Sexually antagonistic polymorphism in simultaneous hermaphroditesDominance of Deleterious Alleles Controls the Response to a Population BottleneckThe Genetic Cost of Neanderthal Introgression.The Strength of Selection against Neanderthal Introgression.Estimating the selective effects of heterozygous protein-truncating variants from human exome data.Trade-off between selection for dosage compensation and masculinization on the avian Z chromosomeDistance from sub-Saharan Africa predicts mutational load in diverse human genomes.When natural selection gives gene function the cold shoulder.Estimating the mutation load in human genomesAccumulation of spontaneous mutations in the ciliate Tetrahymena thermophilaPopulation growth inflates the per-individual number of deleterious mutations and reduces their mean effect.Hitchhiking of deleterious alleles and the cost of adaptation in partially selfing species.The interaction between selection, demography and selfing and how it affects population viability.A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans.Cassava haplotype map highlights fixation of deleterious mutations during clonal propagation.The double edged sword: The demographic consequences of the evolution of self-fertilization.The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives.Evolution of haploid-diploid life cycles when haploid and diploid fitnesses are not equal.Strong dominance of functional alleles over gene deletions in both intensely growing and deeply starved yeast cells.The evolution of selfing is accompanied by reduced efficacy of selection and purging of deleterious mutationsSelective Strolls: Fixation and Extinction in Diploids Are Slower for Weakly Selected Mutations Than for Neutral OnesIncomplete dominance of deleterious alleles contributes substantially to trait variation and heterosis in maize.Sex-chromosome turnovers induced by deleterious mutation load.The interplay of demography and selection during maize domestication and expansion.Environmental stress increases selection against and dominance of deleterious mutations in inbred families of the Pacific oyster Crassostrea gigas.Bioinformatically predicted deleterious mutations reveal complementation in the interior spruce hybrid complex.Evolutionary rescue in randomly mating, selfing, and clonal populations.Expansion load: recessive mutations and the role of standing genetic variation.Consequences of genetic linkage for the maintenance of sexually antagonistic polymorphism in hermaphrodites.
P2860
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P2860
Inferences about the distribution of dominance drawn from yeast gene knockout data.
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2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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Inferences about the distribution of dominance drawn from yeast gene knockout data.
@ast
Inferences about the distribution of dominance drawn from yeast gene knockout data.
@en
type
label
Inferences about the distribution of dominance drawn from yeast gene knockout data.
@ast
Inferences about the distribution of dominance drawn from yeast gene knockout data.
@en
prefLabel
Inferences about the distribution of dominance drawn from yeast gene knockout data.
@ast
Inferences about the distribution of dominance drawn from yeast gene knockout data.
@en
P2860
P1433
P1476
Inferences about the distribution of dominance drawn from yeast gene knockout data.
@en
P2093
Aneil F Agrawal
P2860
P304
P356
10.1534/GENETICS.110.124560
P407
P577
2010-11-23T00:00:00Z