Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
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Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs.The Genetic Cost of Neanderthal Introgression.A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets.Excess of genomic defects in a woolly mammoth on Wrangel island.Estimating the selective effects of heterozygous protein-truncating variants from human exome data.Reflections on the Field of Human Genetics: A Call for Increased Disease Genetics TheorySelection and explosive growth alter genetic architecture and hamper the detection of causal rare variants.A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans.The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives.When Is Selection Effective?Resolving the Conflict Between Associative Overdominance and Background Selection.The population genetics of human disease: The case of recessive, lethal mutations.Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing.Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.Prioritization of Variants Detected by Next Generation Sequencing According to the Mutation Tolerance and Mutational Architecture of the Corresponding Genes.Understanding the Hidden Complexity of Latin American Population Isolates
P2860
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P2860
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
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2015年论文
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2015年论文
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name
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@ast
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@en
type
label
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@ast
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@en
prefLabel
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@ast
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@en
P2093
P2860
P1433
P1476
Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck
@en
P2093
Christopher A Cassa
Daniel J Balick
David Reich
Shamil R Sunyaev
P2860
P304
P356
10.1371/JOURNAL.PGEN.1005436
P577
2015-08-28T00:00:00Z