Hyperphosphorylation of EBNA2 by Epstein-Barr virus protein kinase suppresses transactivation of the LMP1 promoter.
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Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic SignalingAsymmetric Arginine dimethylation of Epstein-Barr virus nuclear antigen 2 promotes DNA targeting.Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit.RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus.A locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteinsHerpes simplex virus 1-encoded protein kinase UL13 phosphorylates viral Us3 protein kinase and regulates nuclear localization of viral envelopment factors UL34 and UL31cdc2/cyclin B1-dependent phosphorylation of EBNA2 at Ser243 regulates its function in mitosis.BGLF4 kinase modulates the structure and transport preference of the nuclear pore complex to facilitate nuclear import of Epstein-Barr virus lytic proteinsPhosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-MCM6-MCM7 complex during Epstein-Barr virus productive replication.Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP.EBNA2 interferes with the germinal center phenotype by downregulating BCL6 and TCL1 in non-Hodgkin's lymphoma cellsEpstein-Barr virus BGLF4 kinase induces premature chromosome condensation through activation of condensin and topoisomerase II.Epstein-Barr virus-encoded protein kinase (BGLF4) is involved in production of infectious virus.Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replicationEpstein-Barr virus protein kinase BGLF4 targets the nucleus through interaction with nucleoporins.Epstein-Barr virus BGLF4 kinase downregulates NF-κB transactivation through phosphorylation of coactivator UXT.Key motifs in EBV (Epstein-Barr virus)-encoded protein kinase for phosphorylation activity and nuclear localization.Conserved herpesvirus protein kinases.Epstein-Barr virus BGLF4 kinase induces disassembly of the nuclear lamina to facilitate virion productionEpstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathwayHsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cellsProtein array identification of substrates of the Epstein-Barr virus protein kinase BGLF4Development of drugs for Epstein-Barr virus using high-throughput in silico virtual screeningThe Epstein-Barr virus protein kinase BGLF4 and the exonuclease BGLF5 have opposite effects on the regulation of viral protein production.Phosphorylation events during viral infections provide potential therapeutic targets.Simian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant.Maribavir inhibits epstein-barr virus transcription in addition to viral DNA replicationEpstein-Barr virus protein kinase BGLF4 is a virion tegument protein that dissociates from virions in a phosphorylation-dependent process and phosphorylates the viral immediate-early protein BZLF1.SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function.Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replication.The regulatory role of protein phosphorylation in human gammaherpesvirus associated cancers.
P2860
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P2860
Hyperphosphorylation of EBNA2 by Epstein-Barr virus protein kinase suppresses transactivation of the LMP1 promoter.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@ast
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@en
type
label
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@ast
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@en
prefLabel
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@ast
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@en
P2860
P1433
P1476
Hyperphosphorylation of EBNA2 ...... tivation of the LMP1 promoter.
@en
P2093
Joseph S Pagano
P2860
P304
P356
10.1128/JVI.79.9.5880-5885.2005
P577
2005-05-01T00:00:00Z