The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration - Wikidata - wikimedia - TriplyDB

The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration

The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration

http://www.wikidata.org/entity/Q33757910

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K+ and Cl- channels and transporters in sperm function Barriers to inhaled gene therapy of obstructive lung diseases: A review Molecular diversity and regulation of renal potassium channels.Inter-α-inhibitor blocks epithelial sodium channel activation and decreases nasal potential differences in ΔF508 mice.The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.Functional interaction between CFTR and the sodium-phosphate co-transport type 2a in Xenopus laevis oocytes Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.Towards the pharmacogenomics of cystic fibrosis.Regulation of the epithelial sodium channel by accessory proteins Pharmacological approaches to correcting the ion transport defect in cystic fibrosis.Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation.ENaCs and ASICs as therapeutic targets.Cell and gene therapy for genetic diseases: inherited disorders affecting the lung and those mimicking sudden infant death syndrome Can intervention in inositol phosphate signalling pathways improve therapy for cystic fibrosis?Regulation of the epithelial Na+ channel by peptidases.Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice.Assessment of the CFTR and ENaC association.Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection.Does epithelial sodium channel hyperactivity contribute to cystic fibrosis lung disease?Endogenous ATP release inhibits electrogenic Na⁺ absorption and stimulates Cl⁻ secretion in MDCK cells.Repairing the basic defect in cystic fibrosis - one approach is not enough.CFTR structure and function: is there a role in the kidney?Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells.Physiological significance of hypotonicity-induced regulatory volume decrease: reduction in intracellular Cl- concentration acting as an intracellular signaling.Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with gamma-ENaC.Inhibition of ENaC by intracellular Cl- in an MDCK clone with high ENaC expression.Cystic fibrosis transmembrane conductance regulator modulates neurosecretory function in pulmonary neuroendocrine cell-related tumor cell line models.The CFTR and ENaC debate: how important is ENaC in CF lung disease?Vasopressin-stimulated CFTR Cl- currents are increased in the renal collecting duct cells of a mouse model of Liddle's syndrome.δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes.Genistein restores functional interactions between Delta F508-CFTR and ENaC in Xenopus oocytes.Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel.Nasal epithelium potential difference at high altitude (4,559 m): evidence for secretion.Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm.Therapeutic attenuation of the epithelial sodium channel with a SPLUNC1-derived peptide in airway diseases.Abnormal regulatory interactions of I148T-CFTR and the epithelial Na+ channel in Xenopus oocytes.CFTR fails to inhibit the epithelial sodium channel ENaC expressed in Xenopus laevis oocytes.

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P2860

The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentration

http://www.wikidata.org/entity/Q33757910

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2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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The cystic fibrosis transmembr ...... ntracellular Cl- concentration

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The cystic fibrosis transmembr ...... ntracellular Cl- concentration

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The cystic fibrosis transmembr ...... ntracellular Cl- concentration

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The cystic fibrosis transmembr ...... ntracellular Cl- concentration

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J König

http://www.w3.org/2001/XMLSchema#string

K Kunzelmann

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M Mall

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R Schreiber

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T Voelcker

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P2860

Two highly homologous members of the ClC chloride channel family in both rat and human kidney

Non-specific activation of the epithelial sodium channel by the CFTR chloride channel

The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na+ channel.

Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.

Feedback inhibition of epithelial Na(+) channels in Xenopus oocytes does not require G(0) or G(i2) proteins.

The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.

cAMP stimulates CFTR-like Cl- channels and inhibits amiloride-sensitive Na+ channels in mouse CCD cells.

CFTR as a cAMP-dependent regulator of sodium channels.

Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function.

Inhibition of amiloride-sensitive epithelial Na(+) absorption by extracellular nucleotides in human normal and cystic fibrosis airways.

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11

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11606421

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cystic fibrosis

transmembrane protein

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