Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.
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Nedd4-2 and the regulation of epithelial sodium transportRole of the UPS in Liddle syndromeThe Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channelPhosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expressionDifferential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channelsPermeability properties of ENaC selectivity filter mutantsAll three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+Regulation and dysregulation of epithelial Na+ channelsRegulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting proteinStimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunitPOSH stimulates the ubiquitination and the clathrin-independent endocytosis of ROMK1 channels.The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl- concentrationFunctional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels.Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.PharmGKB summary: Diuretics pathway, pharmacodynamics.Epithelial Na⁺ sodium channels in magnocellular cells of the rat supraoptic and paraventricular nucleiVariable ratio of permeability to gating charge of rBIIA sodium channels and sodium influx in Xenopus oocytes.Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel.Electrolyte transport in the mammalian colon: mechanisms and implications for disease.Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport.Na+ inhibits the epithelial Na+ channel by binding to a site in an extracellular acidic cleftExternal Cu2+ inhibits human epithelial Na+ channels by binding at a subunit interface of extracellular domains.Intracellular Na+ controls cell surface expression of Na,K-ATPase via a cAMP-independent PKA pathway in mammalian kidney collecting duct cells.ENaC structure and function in the wake of a resolved structure of a family member.Intracellular Na+ regulates epithelial Na+ channel maturation.Feedback inhibition of ENaC: acute and chronic mechanismsUbiquitylation of ion channels.Na(+)-H(+) exchange in salivary secretory cells is controlled by an intracellular Na(+) receptor.Na self inhibition of human epithelial Na channel: temperature dependence and effect of extracellular proteases.Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel.The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels.The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation.Extracellular chloride regulates the epithelial sodium channel.Feedback inhibition of epithelial Na(+) channels in Xenopus oocytes does not require G(0) or G(i2) proteins.Coordinated Control of ENaC and Na+,K+-ATPase in Renal Collecting Duct.Differential sodium and potassium transport selectivities of the rice OsHKT2;1 and OsHKT2;2 transporters in plant cells.Intracellular sodium regulates proteolytic activation of the epithelial sodium channel.Effect of dietary salt intake on epithelial Na+ channels (ENaC) in vasopressin magnocellular neurosecretory neurons in the rat supraoptic nucleus.In vitro phosphorylation of COOH termini of the epithelial Na(+) channel and its effects on channel activity in Xenopus oocytes.
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P2860
Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Mutations causing Liddle syndr ...... opus oocyte expression system.
@en
Mutations causing Liddle syndr ...... opus oocyte expression system.
@nl
type
label
Mutations causing Liddle syndr ...... opus oocyte expression system.
@en
Mutations causing Liddle syndr ...... opus oocyte expression system.
@nl
prefLabel
Mutations causing Liddle syndr ...... opus oocyte expression system.
@en
Mutations causing Liddle syndr ...... opus oocyte expression system.
@nl
P2093
P2860
P356
P1476
Mutations causing Liddle syndr ...... nopus oocyte expression system
@en
P2093
P2860
P304
P356
10.1172/JCI2837
P407
P577
1998-06-01T00:00:00Z