The p53 tumour suppressor inhibits glucocorticoid-induced proliferation of erythroid progenitors.
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Progress towards mechanism-based treatment for Diamond-Blackfan anemiaFrom stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modificationsResponse kinetics of radiation-induced micronucleated reticulocytes in human bone marrow culture.Chronic restraint stress upregulates erythropoiesis through glucocorticoid stimulation.p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expressionIn vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors.ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53.Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs.ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells.TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients.Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.p53 is balancing development, differentiation and de-differentiation to assure cancer prevention.Role of stem cell factor in the reactivation of human fetal hemoglobin.Role of Rho kinases in abnormal and normal hematopoiesis.The notch pathway positively regulates programmed cell death during erythroid differentiation.Pathogenesis of the erythroid failure in Diamond Blackfan anaemia.Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus.Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation.HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity.
P2860
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P2860
The p53 tumour suppressor inhibits glucocorticoid-induced proliferation of erythroid progenitors.
description
2002 nî lūn-bûn
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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2002 թվականի մայիսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
The p53 tumour suppressor inhi ...... tion of erythroid progenitors.
@ast
The p53 tumour suppressor inhi ...... tion of erythroid progenitors.
@en
type
label
The p53 tumour suppressor inhi ...... tion of erythroid progenitors.
@ast
The p53 tumour suppressor inhi ...... tion of erythroid progenitors.
@en
prefLabel
The p53 tumour suppressor inhi ...... tion of erythroid progenitors.
@ast
The p53 tumour suppressor inhi ...... tion of erythroid progenitors.
@en
P2860
P356
P1433
P1476
The p53 tumour suppressor inhi ...... ation of erythroid progenitors
@en
P2093
Gitali Ganguli
Jonathan Back
P2860
P304
P356
10.1093/EMBO-REPORTS/KVF114
P577
2002-05-24T00:00:00Z