about
Explaining oscillations and variability in the p53-Mdm2 systemRegulation of p53 stability and function by the deubiquitinating enzyme USP42A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutantsTwo sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysisSmall-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapyA panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53Differential regulation of EphA2 in normal and malignant cellsLow density DNA microarray for detection of most frequent TP53 missense point mutationsInterference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanismsProtein design: toward functional metalloenzymesCancer prevention with promising natural products: mechanisms of action and molecular targetsAdvances in carcinogenic metal toxicity and potential molecular markersTransitions at CpG dinucleotides, geographic clustering of TP53 mutations and food availability patterns in colorectal cancerImpact of low-frequency hotspot mutation R282Q on the structure of p53 DNA-binding domain as revealed by crystallography at 1.54 Å resolutionDiscovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical DevelopmentDiscovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical DevelopmentMutational signatures associated with tobacco smoking in human cancerMolecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple MyelomaReexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effectMaternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progressionActivation and activities of the p53 tumour suppressor proteinmRNA Display Selection of an Optimized MDM2-Binding Peptide That Potently Inhibits MDM2-p53 InteractionEpigenetic effects of cadmium in cancer: focus on melanomaDNA damage response genes and the development of cancer metastasisOccupational exposure and lung cancerSignificant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug TreatmentUse of high-throughput RT-qPCR to assess modulations of gene expression profiles related to genomic stability and interactions by cadmiumModes of p53 regulationTargeting MDM2 for Treatment of Adenoid Cystic Carcinoma.Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.Regulators associated with clinical outcomes revealed by DNA methylation data in breast cancer.Protein disorder in the human diseasome: unfoldomics of human genetic diseases.p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element.Discovery of 4-((3'R,4'S,5'R)-6″-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2″-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3″-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine DoubleSystematic analysis of genotype-specific drug responses in cancer.Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burdenRedox regulatory mechanisms in cellular stress responses.New targets for the treatment of follicular lymphoma.
P2860
Q21202791-0D216AA4-EAA5-4291-BED9-77B57FAD1598Q24297440-CBEDE1C3-CBF6-4986-8041-D2F65E22FDD8Q24530763-165A24DD-FC1C-4077-9AB5-AD86036ABD6DQ24533476-44DE7128-8546-4726-A7CC-4317E5EAC755Q24645186-6C492AD2-1BE2-4FBF-AA3A-2A5AF90EF1A9Q24651380-D8E0D86E-19C3-4D2C-B410-8E500DAC74EBQ24657532-5CD74698-205E-42AF-AAF5-88EF1C5DC234Q24684095-C5F51D6F-893A-4412-8850-6F135C7D7C80Q24799498-A2212945-C480-434B-BE54-E5A2E726140AQ24812521-FB4F83E0-7628-4197-8570-0AAA63E3220CQ26866201-84FB4A7E-A5B8-4034-AD7A-BC2567B01317Q27006530-37E4A697-565D-40AA-B2FE-ECDA24B805CCQ27015019-C1E10BAC-57B3-4647-8755-139B3ACD1F1AQ27342770-9659A873-93F0-4E0F-94C4-07586F9ACD6BQ27650503-C0F62035-9705-4599-89C2-6AF8EE4816F9Q27684199-1EFAC557-E89F-470B-A399-E7D60C338D17Q27684218-E1EBE417-75AB-4ABD-9F79-802C40B70EC1Q28005544-B4023BE0-A64D-4A46-B668-98E3870F2DE9Q28074490-1ADF9DD7-19F3-41EA-AAD9-B87A2B8BF4FBQ28077883-84E52010-BFB9-47E4-85DB-3AED6E9196B1Q28115872-749364E2-79AD-4F34-8536-5BCA27BFEC60Q28366563-9970F275-FC22-4ACF-B623-69079AB42A9BQ28386936-BD4D473A-5F14-4951-A34F-7A198F07EE97Q28386972-A21997FA-ACC4-4154-9303-E583ABB3D237Q28388312-44E53898-F299-4C9B-8AC3-2EBA9CE2AE08Q28389471-814881AA-420C-4DBE-AAA0-3A286C67878AQ28548249-3ACC64A9-6085-476C-8316-0F60164FAE26Q28821954-2C3B194B-57F4-4410-9AEC-13BDB74D7C10Q29615657-80B3FF80-6C1D-4936-9BA8-7466AABE75D6Q30277227-4115B42A-838D-4DA9-A6B5-496C2087EB22Q30354662-D52D61E8-0D87-4F8F-A1A4-96B3889E571EQ30360723-F0A15881-B0D4-4B2D-B3DB-71E628E375E9Q30956005-92B4D32E-6B36-4C65-AEFF-2F0131E87B8EQ33481211-E047DAD6-7CF7-4AA6-8F00-97EBD74FD1C5Q33569713-F5198855-7E75-4B08-A8EA-F7073B6A6741Q33572704-9A4B5651-E691-4D2E-AE4F-761C344003BCQ33575305-81757BAD-BD82-4E87-9392-56A617DCD6C2Q33576170-87311087-D732-4404-BB1A-7E7375101D98Q33578637-B7B8670F-E7EC-47C2-8F8A-EEA73665756EQ33587396-BC079EFA-90B9-4BC0-967F-CA0799BACD58
P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
p53 and human cancer: the first ten thousand mutations.
@ast
p53 and human cancer: the first ten thousand mutations.
@en
type
label
p53 and human cancer: the first ten thousand mutations.
@ast
p53 and human cancer: the first ten thousand mutations.
@en
prefLabel
p53 and human cancer: the first ten thousand mutations.
@ast
p53 and human cancer: the first ten thousand mutations.
@en
P1476
p53 and human cancer: the first ten thousand mutations
@en
P2093
M Hollstein
P304
P577
2000-01-01T00:00:00Z