Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors. - Wikidata - wikimedia - TriplyDB

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

http://www.wikidata.org/entity/Q33758339

about

Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data.Limiting the power of p53 through the ubiquitin proteasome pathway.Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells Interference with mutagenic aflatoxin B1-induced checkpoints through antagonistic action of ochratoxin A in intestinal cancer cells: a molecular explanation on potential risk of crosstalk between carcinogens.Mouse modelling of the MDM2/MDMX-p53 signalling axis.Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.To clear, or not to clear (senescent cells)? That is the question.

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P2860

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

http://www.wikidata.org/entity/Q33758339

description

2014 nî lūn-bûn

@nan

2014 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

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2014年學術文章

@yue

name

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

@ast

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

@en

type

label

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

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Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

@en

prefLabel

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

@ast

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

@en

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1541-7786.MCR-14-0089

P1433

Molecular Cancer Research

P1476

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors

@en

P2093

Adel K El-Naggar

http://www.w3.org/2001/XMLSchema#string

Gilda Chau

http://www.w3.org/2001/XMLSchema#string

Guillermina Lozano

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Peirong Yang

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Qin Li

http://www.w3.org/2001/XMLSchema#string

Shunbin Xiong

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Yun Zhang

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P2860

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Restoration of p53 function leads to tumour regression in vivo

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis.

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor.

Modeling the therapeutic efficacy of p53 restoration in tumors.

Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation.

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901-911

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scholarly article

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10.1158/1541-7786.MCR-14-0089

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6

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12

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James G Jackson

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2014-03-05T00:00:00Z

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24598047

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4058386

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