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APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis

APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis

http://www.wikidata.org/entity/Q33759956

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MyD88 deficiency ameliorates β-amyloidosis in an animal model of Alzheimer's disease Protein phosphatases and Alzheimer's disease Toward more predictive genetic mouse models of Alzheimer's disease Dissecting Alzheimer disease in Down syndrome using mouse models The Beta-amyloid protein of Alzheimer's disease: communication breakdown by modifying the neuronal cytoskeleton Neuropathological alterations in Alzheimer disease Loss of Polo ameliorates APP-induced Alzheimer's disease-like symptoms in Drosophila Neurodegenerative disease and adult neurogenesis The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice.Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer.Impaired structural correlates of memory in Alzheimer's disease mice.A review of β-amyloid neuroimaging in Alzheimer's disease.Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice.The neurovascular unit in brain function and disease.Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex Molecular mechanisms of neurodegeneration in Alzheimer's disease.Neurotoxicity of cancer chemotherapy.Knockdown of amyloid precursor protein in zebrafish causes defects in motor axon outgrowth.Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10.Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis The pathological roles of ganglioside metabolism in Alzheimer's disease: effects of gangliosides on neurogenesis.Temporal profiles of synaptic plasticity-related signals in adult mouse hippocampus with methotrexate treatment.CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-β plaques in an Alzheimer's disease mouse model.The use of mouse models for understanding the biology of down syndrome and aging Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus.Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer's disease Turmeric and curcumin suppress presenilin 1 protein expression in Jurkat cells Abca7 deletion does not affect adult neurogenesis in the mouse.Generation of a novel murine model of Aβ deposition based on the expression of human wild-type amyloid precursor protein gene.LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease.Current Opinion on the Role of Neurogenesis in the Therapeutic Strategies for Alzheimer Disease, Parkinson Disease, and Ischemic Stroke; Considering Neuronal Voiding Function.The multiplicity of action of cannabinoids: implications for treating neurodegeneration.Neurogenesis in Alzheimer's disease.Modeling human neurodegenerative diseases in transgenic systems.The influence of cannabinoids on generic traits of neurodegeneration.Cognitive reserve and Alzheimer's disease.Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer's Disease: in Search of a Relevant Mechanism.Adult neurogenesis in neurodegenerative diseases.Tau-dependent suppression of adult neurogenesis in the stressed hippocampus.

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APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis

http://www.wikidata.org/entity/Q33759956

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name

APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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type

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APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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Brain Structure and Function

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APP transgenic modeling of Alz ...... tion and aberrant neurogenesis

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Leslie Crews

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P2860

Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Purification and cloning of amyloid precursor protein beta-secretase from human brain

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

Neurotoxicity induces cleavage of p35 to p25 by calpain

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Eliezer Masliah

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Alzheimer's disease

Chin-hu̍t seng-bu̍t

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2847155

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